Sort   by:  
 Page size 
Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
GenomicsImmune and Metabolic Features of Brain Metastases Melanoma (Cancer Discovery) Data Access Committee
Data Access Committee EGAC00001001216
EGAC00001001216 | EGA
Genomicsena-DATASET-MDACC-31-10-2017-21:58:14:730-1118 - samples
This dataset contains WES data (.bam files) and associated phenotype information from 10 patients included in our microbiome study who went on to anti PD-1 immunotherapy for the treatment of metastatic melanoma at the University of Texas MD Anderson Cancer Center. Both tumor and matching germ line n...
EGAD00001003797 | EGA
Genomicsena-DATASET-MDACC-02-02-2018-10:54:47:473-560 - samples
The oral and gut microbiomes of melanoma patients were characterized before the initiation of ant-PD1 immunotherapy, and compared to treatment response. Validation studies were performed in germ-free mice using stool from patients who responded/did not respond to ant-PD1 immunotherapy. All baseline...
EGAD00001003943 | EGA
UnknownSpatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.
Not available
S-EPMC7160105 | biostudies-literature
GenomicsGut microbiome modulates response to anti PD1 immunotherapy in metastatic melanoma patients
There is a growing appreciation of the role of the microbiome in cancer, and evidence in pre-clinical models that the gut microbiome may modulate responses to immune checkpoint blockade though this has not been well-characterized in patients. We analyzed the oral (n=86)and gut (n=43) 16S microbiome ...
EGAS00001002698 | EGA
UnknownMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
Not available
S-EPMC6497554 | biostudies-literature
GenomicsThis committee is composed on individuals who have access to the data corresponding to this project: Gut microbiome modulates response to anti PD-1 immunotherapy in melanoma patients
Data Access Committee EGAC00001000758
EGAC00001000758 | EGA
UnknownGenomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
Not available
S-EPMC5557036 | biostudies-literature
Sort   by:  
 Page size