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ProteomicsProteomic analysis of human skeletal micro muscles
Three dimensional engineered culture systems are powerful tools to rapidly expand our knowledge of human biology and identify novel therapeutic targets for disease. Bioengineered skeletal muscle has been recently shown to recapitulate many features of native muscle biology. However, current skeletal...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD011919 | Pride
Skeletal muscle proteomics 
UnknownTDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia.
Not available
S-EPMC8677511 | biostudies-literature
ProteomicsProteomics of vascularized cardiac organoids
Crosstalk between cardiac cells is critical during heart development but its role in organ maturation is still largely uncharacterised. Here, we show that endothelial cells increas the force of contraction and enhance the expression of mature sarcomeric proteins and extracellular matrix (ECM) compon...
ORGANISM(S): Homo sapiens (Human) 
2025-11-06 | PXD019266 | Pride
Cardioac organoids Endothelial cells 
ProteomicsDiscovery of drugs to treat cytokine storm-induced cardiac dysfunction
SARS-CoV2 infection leads to cardiac injury and dysfunction in 20-30% of hospitalized patients and higher rates of mortality in patients with pre-existing cardiovascular disease. Inflammatory factors released as part of the 'cytokine storm' are thought to play a critical role in cardiac dysfunction ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-21 | PXD020994 | Pride
Sars-cov2 Cardiac organoids Cytokine storm Easyphos Phosphoproteomics Covid-19 Heart 
UnknownBET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Not available
S-EPMC7962543 | biostudies-literature
UnknownPI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Not available
S-EPMC10940093 | biostudies-literature
UnknownAn IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease.
Not available
S-EPMC10154240 | biostudies-literature
UnknownA C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.
Not available
S-EPMC6158742 | biostudies-literature
UnknownThe database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project.
Not available
S-EPMC5215197 | biostudies-literature
UnknownElective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
Not available
S-EPMC8189635 | biostudies-literature
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