Huganir Richard L RL

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Proteomics (2)

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pride (2)

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Mass Spectrometry (2)
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2018 (1)
2017 (1)

Lab affiliation

Solomon H. Snyder Department of Neuroscience, Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA (1)
The Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine USA (1)

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Homer1a drives Homeostatic Scaling-down of Excitatory Synapses During Sleep

Homeostatic scaling is a global form of synaptic plasticity used by neurons to adjust overall synaptic weight and maintain neuronal firing rates while protecting information coding. While homeostatic scaling has been demonstrated in vitro, a clear physiological function of this plasticity type has n...

ORGANISM(S): Mus musculus (Mouse)

2017-02-13 | PXD004537 | Pride

Identification of Long Lived Synaptic Proteins by Comprehensive Proteomic Analysis of Synaptosome Protein Turnover

Memory formation is believed result from changes in synapse strength and structure. While memories may persist for the lifetime of an organism, the proteins and lipids that make up synapses undergo constant turnover with lifetimes from minutes to days. The molecular basis for memory maintenance may ...

ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat)

2018-03-19 | PXD007156 | Pride

Protein turnover Long lived protein Synaptosome

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