Sort   by:  
 Page size 
TranscriptomicsCG methylated microarrays identify novel methylated sequence bound by the CEBPB|ATF4 heterodimer that are active in vivo
To evaluate the effect of CG methylation on DNA binding of sequence-specific B-ZIP transcription factors (TFs) in a high-throughput manner, we enzymatically methylated the cytosine in the CG dinucleotide on protein binding microarrays. Two Agilent DNA array designs were used. One contained 40,000 ...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-44338 | biostudies-arrayexpress
UnknownCG gene body DNA methylation changes and evolution of duplicated genes in cassava.
Not available
S-EPMC4640745 | biostudies-literature
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
UnknownInvolvement of a Jumonji-C domain-containing histone demethylase in DRM2-mediated maintenance of DNA methylation.
Not available
S-EPMC2999860 | biostudies-literature
TranscriptomicsIdentification of transcripts regulated by CEBPA protein and its P30 isoform in K562
To investigate the effect of CEBPA and its mutant isoform P30 on the expression of mRNAs and long non-coding RNAs (lncRNAs), we utilized the K562 AML cell line carrying a stable and Tet-on inducible CEBPA or P30 allele. Based on the expression of known CEBPA transcriptional targets, we selected RNA...
ORGANISM(S): Homo sapiens 
2015-06-10 | E-GEOD-65235 | biostudies-arrayexpress
UnknownMutation Signatures Including APOBEC in Cancer Cell Lines.
Not available
S-EPMC5993214 | biostudies-literature
TranscriptomicsVariation in homeodomain DNA-binding revealed by high-resolution analysis of sequence preferences
Most homeodomains are unique within a genome, yet many are highly conserved across vast evolutionary distances, implying strong selection on their precise DNA-binding specificities. We determined the binding preferences of the majority (168) of mouse homeodomains to all possible 8-base sequences, re...
ORGANISM(S): Mus musculus 
2010-06-26 | E-GEOD-11239 | biostudies-arrayexpress
UnknownMethyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA.
Not available
S-EPMC5150381 | biostudies-literature
TranscriptomicsSMAUG Is a Major Regulator of Maternal mRNA Destabilization in Drosophila
In animals, egg activation triggers a cascade of posttranscriptional events that act on maternally synthesized RNAs. We show that, in Drosophila, the PAN GU (PNG) kinase sits near the top of this cascade, triggering translation of SMAUG (SMG), a multifunctional posttranscriptional regulator conserve...
ORGANISM(S): Drosophila melanogaster 
2007-09-13 | E-GEOD-8910 | biostudies-arrayexpress
ProteomicsFeeling hot headed: Quantitative proteomic profiling reveals region specific brain responses to elevated water temperature in Atlantic salmon (Salmo salar L.)
Increasing summer seawater temperatures in Tasmania pose a significant challenge to Atlantic salmon aquaculture. While several studies have investigated the physiological impacts of thermal stress, the molecular mechanisms underlying brain-region-specific adaptation remain unexplored. Understanding ...
ORGANISM(S): Salmo salar (Atlantic salmon) 
2026-09-14 | PXD070727 | Pride
Proteomics Atlantic salmon Brain regions Elevated temperature 
Sort   by:  
 Page size