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TranscriptomicsTranscription profiling of human hepatocellular carincoma-derived cell line Huh7-S33Y with high TCF activity compared to a control Huh7 cell line
The Wnt signaling pathway is involved in many differentiation events during embryonic development and can lead to tumor formation after aberrant activation of its components. Β-catenin, a cytoplasmic component, plays a major role in the transduction of the canonical wnt/ β-catenin signaling. The aim...
ORGANISM(S): Homo sapiens 
2009-10-10 | E-GEOD-11916 | biostudies-arrayexpress
TranscriptomicsComparison of TCF hyper-activated and control Huh7 cells
This SuperSeries is composed of the following subset Series: GSE11912: Comparison of TCF hyper-activated and control Huh7 cells - SAGE GSE11916: Comparison of TCF hyper-activated and control Huh7 cells - microarray data Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-05-22 | E-GEOD-11956 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of Huh7 cells treated with IFNa2, OSM or IFNa2 combined with OSM
OSM increases the antiviral effect of IFNα in Huh7 cells infected with hepatitis A virus (HAV) or HCV replicon and synergizes with IFNα in the induction of antiviral genes 16 samples. Four replicates for each experimental condition. 72 hours of treatment in DMEM supplemented with 2% FBS.
ORGANISM(S): Homo sapiens 
2009-01-20 | E-GEOD-13046 | biostudies-arrayexpress
TranscriptomicsExpression levels of mature miRNAs from Huh7 cell treated with ROCK inhibitor
We used microarray to determine the miRNA whose expression was changed at 12 hours after Y27632 treatment Two-condition experiment; Huh7 control vs Huh7 treated with Y27632 for 12 hours
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-33876 | biostudies-arrayexpress
TranscriptomicsHuh7 cells exist as a mixed population of cells with distinct patterns of gene methylation
A powerful approach to study innate antiviral response is to compare the difference between wild type Huh7 cells, which do not support robust replication of hepatitis C virus (HCV)2, versus certain subclones of Huh7 cells that are permissive for HCV replication. We generated two permissive cell line...
ORGANISM(S): Homo sapiens 
2013-07-03 | E-GEOD-31960 | biostudies-arrayexpress
TranscriptomicsExpression data comparing Huh7 control and CD47 knockdown cells
To identify candidate genes regulated by CD47 Affymetrix Human Genome U133 Plus GeneChip 2.0 HCC cell line Huh7 cells with or without CD47 repressed
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-47563 | biostudies-arrayexpress
TranscriptomicsComparison of TCF hyper-activated and control Huh7 cells - SAGE
The Wnt signaling pathway is involved in many differentiation events during embryonic development and can lead to tumor formation after aberrant activation of its components. ?-catenin, a cytoplasmic component, plays a major role in the transduction of the canonical wnt/ ?-catenin signaling. The aim...
ORGANISM(S): Homo sapiens 
2009-09-30 | E-GEOD-11912 | biostudies-arrayexpress
TranscriptomicsTrancription profiling of the hepatoma cell line Huh7 infected with the Hepatitis C Virus
Hepatitis C Virus is a leading cause of chronic liver disease. The identification and characterisation of key host cellular factors that play a role in the HCV replication cycle is important for the understanding of disease pathogenesis and the identification of novel anti-viral therapeutic targets....
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20948 | biostudies-arrayexpress
TranscriptomicsExpression data comparing Huh7 cells transduced with shRNA CD24 (knockdown) or non-target control
To identify CD24 signaling pathway Affymetrix Human Genome U133 Plus GeneChip 2.0 shRNA CD24 (knockdown) or non-target control (NTC) was stably transduced into Huh7 HCC cells by lentiviral approach
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-28057 | biostudies-arrayexpress
TranscriptomicsMicroRNA (miRNA) expression profile in Huh7 cells treated with siRNA targeting nuclear factor 90 (siNF90)
Our previous study has showed that complex of NF90 and nuclear factor 45 (NF45) (NF90-NF45) inhibits miRNA biogenesis through negative regulation of primary-miRNA processing step. On the other hand, miRNAs, the biogenesis of which is regulated by NF90-NF45 in hepatocellular carcinoma, are not clear....
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-67411 | biostudies-arrayexpress
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