Huh7 p62 ko - OmicsDI

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Development of a p62 biodegrader for autophagy targeted degradation

Harnessing autophagy for targeted degradation of intracellular cargo is a promising extension to proteasome-based targeted protein degradation because of the capacity and versatility of lysosomes, broadening the scope of therapeutic targets. First autophagy-based degraders and glues have been identi...

ORGANISM(S): Homo sapiens (Human)

2025-10-16 | PXD057810 | Pride

Huh7 p62 ko Huh7

Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria.

Not available

S-EPMC9157002 | biostudies-literature

The role of a novel CAR-induced gene TUBA8 in hepatocellular carcinoma cell lines

The Tuba8 gene was identified as a CAR-regulated gene that was induced during phenobarbital (PB) promotion of liver tumor. TUBA8 was then over-expressed in heaptocarcinoma cells to determine the function of TUBA8. First, identify genes that are regulated by CAR and are induced during liver tumor dev...

ORGANISM(S): Mus musculus

2011-11-29 | E-GEOD-29108 | biostudies-arrayexpress

Identification of Ligands for the human gamma-delta TCR

T cells bearing gamma delta T cell antigen receptors (TCRs) function in lymphoid stress surveillance. However, the contribution of gamma delta TCRs to such responses is unclear. Here we found that the TCR of a human V gamma4Vdelta5 clone directly bound endothelial protein C receptor (EPCR), which al...

ORGANISM(S): Homo sapiens

2012-07-27 | E-GEOD-39709 | biostudies-arrayexpress

Open Chromatin by DNaseI HS from ENCODE/OpenChrom(Duke University)

This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Terry Furey mailto:tsfurey@duke.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). These tracks displa...