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ProteomicsAdenovirus particles SILAC analysis of different batches and mutant virus
We used stable isotope labelling of amino acids in cell culture coupled with high throughput quantitative mass spectrometry to analyse the protein composition of highly purified wild type adenoviruses, mutant adenoviruses lacking an internal protein component (protein V) and recombinant adenoviruses...
ORGANISM(S): Homo sapiens (Human) 
2014-08-08 | PXD001120 | Pride
Human adenovirus purified particles 
ProteomicsHuman Adenovirus 5 (HAdV5), LC-MSMS
Using high-resolution mass spectrometry (MS)-based proteomics in combination with multiple protease digestion, we profiled, with on average 90% sequence coverage, all 13 viral proteins present in an human adenovirus (HAdV) vector. This in-depth profile provided multiple peptide-based evidence on int...
ORGANISM(S): Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) 
2014-06-09 | PXD000591 | Pride
Proteomics Adenovirus Quantification 
OtherAnalysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics.
Data from ProteomeXchange, PXD ID: PXD001120. File: 10_2.mzml. Published as part of J Gen Virol. 2014 Aug 5 . From the Abstract: {{i}} We used stable isotope labelling of amino acids in cell culture and high throughput quantitative mass spectrometry to analyse the protein composition of highly puri...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310002885 | GPMDB
Resource Reanalysis 
UnknownReduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.
Not available
S-EPMC3503036 | biostudies-literature
TranscriptomicsStimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by Nkx6.1
The homeodomain transcription factor Nkx6.1 plays an important role in pancreatic islet β-cell development, but its effects on adult β-cell function, survival, and proliferation are not well understood. In the present study, we demonstrated that treatment of primary rat pancreatic islets with a cy...
ORGANISM(S): Rattus norvegicus 
2010-05-18 | E-GEOD-13153 | biostudies-arrayexpress
UnknownStepwise loss of fluorescent core protein V from human adenovirus during entry into cells.
Not available
S-EPMC3014209 | biostudies-literature
TranscriptomicsVirus-misplaced host protein activates innate immunity
Discrimination between self vs. non-self and adequate response to infection and tissue damage are fundamental functions of the immune system. The rapid and global spread of known and emerging viruses is a testament that the timely detection of viral pathogens that reproduce within host cells, presen...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-36078 | biostudies-arrayexpress
UnknownA humanized anti-human adenovirus 55 monoclonal antibody with good neutralization ability.
Not available
S-EPMC10060833 | biostudies-literature
ProteomicsCryo-electron tomography and proteomics identify a virus structure poised for genome uncoating
Viral infections invariably require the dismantling of capsids enclosing viral genomes. Yet, discrete intermediates and host factors supporting nucleic acid uncoating in susceptible cells are largely elusive. Using cryo-electron tomography (cryo-ET) and superresolution microscopy we show that human ...
ORGANISM(S): Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) Homo sapiens (Human) 
2026-04-14 | PXD076818 | Pride
UnknownPenton-dodecahedral particles trigger opening of intercellular junctions and facilitate viral spread during adenovirus serotype 3 infection of epithelial cells.
Not available
S-EPMC3814681 | biostudies-literature
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