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ProteomicsAurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics.
Precise regulation of kinetochore-microtubules is essential for successful chromosome segregation. Central to this regulation is Aurora B kinase, which phosphorylates kinetochore substrates to promote microtubule turnover. A critical target of Aurora B is the N-terminal “tail” domain of Hec1/NDC80, ...
ORGANISM(S): Homo sapiens (Human) 
2017-11-28 | PXD006892 | Pride
Human aurora a kinase hec1 
UnknownHuman condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation.
Not available
S-EPMC2730017 | biostudies-literature
UnknownchTOG is a conserved mitotic error correction factor.
Not available
S-EPMC7773332 | biostudies-literature
UnknownMeasuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments.
Not available
S-EPMC6089600 | biostudies-literature
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
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