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MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
MetabolomicsThe bile acid metabolome in umbilical cord blood and meconium of healthy newborns: Distinct characteristics and implications (Umbilical cord blood analysis)

OBJECTIVE: To characterize the bile acid (BA) metabolomic profile of umbilical cord blood (UCB) and meconium in healthy newborns.

METHODS: Fifteen healthy newborns, which born in the Obstetrics Department of the Affiliated Hospital of Southwest Medical Univ...

2024-11-28 | MTBLS10266 | MetaboLights
MetabolomicsA blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights
MetabolomicsThe bile acid metabolome in umbilical cord blood and meconium of healthy newborns: Distinct characteristics and implications (Meconium analysis)

OBJECTIVE: To characterize the bile acid (BA) metabolomic profile of umbilical cord blood (UCB) and meconium in healthy newborns.

METHODS: Fifteen healthy newborns, which born in the Obstetrics Department of the Affiliated Hospital of Southwest Medical Univ...

2024-11-28 | MTBLS10267 | MetaboLights
ProteomicsHuman blood LC-MSMS Simple Protein Identification Report
The present study employs Liquid Chromatography-Mass Spectrometry (LC-MS) technology for the identification of proteins, utilizing the Q-Exactive mass spectrometer produced by Thermo Fisher Scientific. Upon the analysis of the ARP1-USP13-OE sample via Proteome Discoverer software, a total of 3631 pe...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD057487 | Pride
Human blood cell lc-msms 
MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2782 | MetaboLights
ProteomicsBlood to plasma processing : time-anticoagulant
This dataset contains raw mass spectrometry data (in the form of Thermo Fisher .RAW files) supporting associated publication “Variable blood processing procedures contribute to plasma proteomic variability” by Halvey et al. The experiments characterized by these data evaluated effects on human plas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-21 | MSV000085799 | MassIVE
ProteomicsBlood plasma and serum samples of healthy donors fractionated on different chromatography sorbents
Blood as connective tissue potentially contain evidence of all processes occurring within the organism, at least in trace amounts. Because of their small size, peptides overcome cell membranes and epithelial barriers more freely than proteins. Among the peptides found in blood, there are both fragme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-15 | MSV000081717 | MassIVE
MetabolomicsComparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. and characteristic pure compounds reveals differential anti-inflammatory effects on human T cells

Introduction

Chronic inflammation is a hallmark of chronic wounds and inflammatory skin diseases. Due to a hyperactive and prolonged inflammation triggered by proinflammatory immune cells, transitioning to the repair and healing phase is halted. T cells may exacerbate the proinflammatory mil...
2025-07-09 | MTBLS9800 | MetaboLights
ProteomicsBlood to plasma processing : centrifugation
This dataset contains raw mass spectrometry data (in the form of Thermo Fisher .RAW files) supporting associated publication “Variable blood processing procedures contribute to plasma proteomic variability” by Halvey et al. The experiments characterized by these data evaluated effects on human plas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-16 | MSV000085763 | MassIVE
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