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ProteomicsA2M Q975C and C3 Q1013C disulfide mutants
Mutant A2M and C3 with disulfides replacing their thiol esters were disulfide mapped via pepsin digests.
ORGANISM(S): Homo sapiens (Human) 
2021-02-18 | PXD019082 | Pride
Human c3 a2m 
UnknownMFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy.
Not available
S-EPMC7350165 | biostudies-literature
TranscriptomicsTranscription profiling of human decidual macrophages
Uterine macrophages are thought to play an important regulatory role at the maternal-fetal interface. We report here a unique gene expression pattern intrinsic of first trimester decidual monocytes/macrophages, but not of their blood counterparts. The micro-array data comprises approximately 14,000 ...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-10612 | biostudies-arrayexpress
UnknownCryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Not available
S-EPMC9156758 | biostudies-literature
ProteomicsSerum Alpha-2-Macroglobulin Links Type 1 Diabetes Status and Incident Cardiovascular Disease
Background: Cardiovascular disease (CVD) is a leading cause of mortality in individuals with type 1 diabetes mellitus (T1DM), with conventional risk factors not fully explaining the heightened risk. Study Design: We conducted a cross-sectional study comparing serum protein levels in 134 participants...
ORGANISM(S): Homo Sapiens 
2025-02-11 | PXD054039 | panorama
UnknownMutations in CPAMD8 Cause a Unique Form of Autosomal-Recessive Anterior Segment Dysgenesis.
Not available
S-EPMC5142107 | biostudies-literature
TranscriptomicsGene regulation in brain, eye and heart of sighted C3H mice
It is unclear what role vision plays in guiding mouse behaviour, since the mouse eye is of comparably low optical quality, and mice are considered to rely primarily on other senses. All C3H substrains are homozygous for the Pde6b(rd1) mutation and get blind by weaning age. To study the impact of the...
ORGANISM(S): Mus musculus 
2010-05-23 | E-GEOD-7855 | biostudies-arrayexpress
TranscriptomicsGene regulation in ki-ras transfected murine fibroblasts
Ki-ras gene mutations are involved in the carcinogenesis of acute myeloid leukemia, melanoma and different carcinomas. In order to define potential mutation-specific therapeutic targets, expression profiling analyses were performed using stable transfected NIH3T3 cells carrying different ki-ras gene...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8372 | biostudies-arrayexpress
TranscriptomicsEyeless: Pitx3 mutant mouse line, Expression profiling of liver
A new mouse mutant arose spontaneously at the 5th inbred generation in a congenic C3H/He line. Since the mice suffered from anophthalmia or microphthalmia, we referred to this new mutant as eyeless (provisional gene symbol: eyl). The mutation follows an autosomal recessive pattern of inheritance and...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-15336 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila Kc167 cells following 5-48 hr treatment with 20-hydroxyecdysone
The changes in transcript titers are described for Drosophila Kc167 cells following 5-48 hr treatment with 20-hydroxyecdysone.
ORGANISM(S): Drosophila melanogaster 
2009-05-01 | E-MEXP-1603 | biostudies-arrayexpress
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