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Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium, and the microbiota. We found that mice lacking B lymphocytes, or lacking IgA, have low intestinal expression of lipid metabolism genes regulated by the transcri...
ORGANISM(S): Homo sapiens 
In order to explore the functions of carbonic anhydrase VI (CAVI) more fully, we examined the transcriptomic responses to CAVI deficiency in the submandibular gland, stomach, and duodenum of Car6-/- mice by cDNA microarray. 94, 56, and 127 genes were up- or down-regulated in the above-mentioned tiss...
ORGANISM(S): Mus musculus 
Affymetrix U95Av2 expression data from human intestinal cells (Caco-2) and tissues from all intestinal segments (duodenum, jejunum, ileum, colon). Entries contain the search terms glycosylase, phosphorylase, cytochrome or nucleoside, which were relevant to our search for enzymes capable of cleaving...
ORGANISM(S): Homo sapiens 
Here, we used single-cell RNA-sequencing (scRNA-seq) to profile intestinal epithelial only organoids (also known as enteroids) from human fetal duodenum after one passage of in vitro growth. Organoids were grown in the standard 25% LWRN media with either 100 ng/ml of EGF or 1 ng/ml of EREG added.
ORGANISM(S): Homo sapiens 
samples contain normal, Berret and duodenum and adenocarcinoma
ORGANISM(S): Homo sapiens 
We use a genome wide transcriptomic approach to assess the effects of C. perfringens toxin infusion in the duodenum of broilers
ORGANISM(S): Gallus gallus 
The upper gastrointestinal tract consisting of the esophagus, stomach and duodenum controls food transport, digestion, nutrient uptake and hormone production. By single-cell analysis of healthy epithelia of these human organs, we molecularly defined their distinct cell types. We identified a quiesce...
scRNA-seq of intestinal epithelial organoids derived from human fetal duodenum
This SuperSeries is composed of the following subset Series: GSE23573: B-cell KO mice data GSE23933: human duodenum biopsy data GSE33884: The role of immunoglobulin A GSE33885: The role of transcription factor Gata4 Refer to individual Series
ORGANISM(S): Mus musculus 
Uhlén2015 - Human tissue-based proteome metabolic network - duodenum Human duodenum specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A,...
2015-01-28 | MODEL1411240027 | BioModels
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