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TranscriptomicsRNA-seq of estrogen (E2) induced changes of mRNA expression in early pregnant Sus scrofa endometrium
Maternal exposure to estrogens can induce long-term adverse effects in the offspring. This may be mediated through alterations in the endometrium affecting embryo-maternal communication as early as the preimplantational phase. Thus, we analyzed the effects of gestational estradiol-17β (E2) exposure ...
ORGANISM(S): Sus scrofa 
2018-10-16 | E-MTAB-6242 | biostudies-arrayexpress
TranscriptomicsComparison of the effects of early pregnancy with human interferon, alpha 2 (IFNA2) on gene expression in bovine endometrium
Interferon tau (IFNT), a Type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal, produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression changes during early pregnancy were compared to ...
ORGANISM(S): Bos taurus 
2011-10-31 | E-GEOD-30694 | biostudies-arrayexpress
TranscriptomicsLow dose human chorionic gonadotropin hCG
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-10-02 | E-GEOD-18557 | biostudies-arrayexpress
TranscriptomicsExpression data of human decidual NK cells from gravid uteri and NK cells from cycling endometrium
Human NK cells from the decidua basalis of gravid uteri (dNK) and from cycling endometrium (eNK) of women undergoing hysterectomy were isolated and compared by gene expression profiling using Affymetrix microarrays with probes representing ~47,400 transcripts. Substantial differences indicate th...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-20499 | biostudies-arrayexpress
TranscriptomicsInteractome of Human Embryo Implantation: Identification of Gene Expression Pathways, Regulation, and Integrated Regulatory Networks.
Possible interactions between endometrium and implanting embryo in humans
ORGANISM(S): Homo sapiens 
2011-12-16 | E-MEXP-3111 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis of endometrium tissue from women with metastatic endometrial cancer.
The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in endometrium tissues from women with metastatic endometrial cancer. Endometrium tissue samples were drawn from 18 metastatic endometrial cancers. The metastati...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-33422 | biostudies-arrayexpress
TranscriptomicsDiscovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circu...
ORGANISM(S): Ovis aries 
2010-05-15 | E-GEOD-17401 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human endometrial endothelial cells of eutopic endometrium of patients with endometriosis compared with control
The pathogenesis of endometriosis may result from aberrant angiogenesis that occurs in eutopic endometrium with retrograde menstruation. The difference in gene expression profile between human endometrial endothelial cells (HEECs) from eutopic endometria of patients with and without endometriosis wo...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7846 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human paired euctopic and ectopic human endometrium from 9 individuals (endometriosis)
The pathophysiology of endometriotic lesion development remains unclear but involves a complex interaction between ectopic endometrium and host peritoneal tissues. We hypothesised that disruption of this interaction was likely to suppress endometriotic lesion formation. We hoped to delineate the mol...
ORGANISM(S): Homo sapiens 
2009-01-02 | E-GEOD-11691 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ectopic endometrium and peritoneal tissues in nude mice
This SuperSeries is composed of the following subset Series:; GSE11691: Euctopic and ectopic human endometrium (endometriosis); GSE11768: Nude mouse model of endometriosis Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-01-02 | E-GEOD-11769 | biostudies-arrayexpress
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