Human induced pluripotent stem cell-derived cardiomyocyte

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Lab affiliation

Charles Perkins Centre, University of Sydney (1)
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Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (1)
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Otto Krayer Professor Department of Systems Biology Head of the Harvard Program in Therapeutic Sciences Harvard Medical School 200 Longwood Avenue, WAB440 Boston, MA 02115 (1)
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Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Göttingen, Germany (1)
University of Wisconsin-Madison (1)

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Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs with high efficiency in chemically defined and xeno-free conditions. Despi...

2018-04-24 | MTBLS425 | MetaboLights

miRNA expression profiling of differentiating human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

To gain insight into the molecular regulation of human heart development, a detailed comparison of the mRNA and miRNA transcriptomes across differentiating human-induced pluripotent stem cell (hiPSC)–derived cardiomyocytes and biopsies from fetal, adult, and hypertensive human hearts was performed. ...

ORGANISM(S): Homo sapiens

2012-02-10 | E-GEOD-35672 | biostudies-arrayexpress

Expression profiling analysis of differentiating human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

This SuperSeries is composed of the following subset Series: GSE35671: Comparison of mRNA expression profiling of differentiating human-induced pluripotent stem cell (hiPSC)–derived cardiomyocytes, biopsies from fetal, adult and hypertensive human hearts and primary cardiomyocytes GSE35672: miRNA ex...

ORGANISM(S): Homo sapiens

2012-02-10 | E-GEOD-35673 | biostudies-arrayexpress

Comparison of mRNA expression profiling of differentiating human-induced pluripotent stem cell (hiPSC)–derived cardiomyocytes, biopsies from fetal, adult and hypertensive human hearts and primary cardiomyocytes

ORGANISM(S): Homo sapiens

2012-02-10 | E-GEOD-35671 | biostudies-arrayexpress

Mitochondrial Transplantation Ameliorates Doxorubicin-Induced Cardiac Dysfunction via Activating Glutamine Metabolism

Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...

2025-03-13 | MTBLS7989 | MetaboLights

Secretome analysis during human induced pluripotent stem cell-derived cardiomyocyte differentiation

PRJNA1424899 | ENA

Comparison of human pluripotent stem cell-derived cardiomyocyte subtypes

PRJNA1256736 | ENA

MicroRNA array profiling on human pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin

Cardiomyocytes derived from human pluripotent stem cells were exposed to the cardiotoxic drug Doxorubicin in order to assess the utility of this cell system as a model for drug-induced cardiotoxicity. Cells are exposed to different concentrations of doxorubicin for up to 48 hours followed by a 12 da...

ORGANISM(S): Homo sapiens

2017-10-28 | E-MTAB-6052 | biostudies-arrayexpress

RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation

PRJNA573883 | ENA

Expression data from human iPS cells treated by a small molecule KY02111

Human pluripotent stem cells (hPSCs) such as embryonic stem cells and induced pluripotent stem cells are promising materials for cell-based regenerative therapies to heart diseases. However, until realization there are many hurdles such as high efficiency of cardiac differentiation of hPSCs and prod...

ORGANISM(S): Homo sapiens

2012-10-30 | E-GEOD-33622 | biostudies-arrayexpress

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