Human lung adenocarcinoma

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Unknown (2656)
Transcriptomics (1821)
Genomics (900)
Proteomics (283)
Other (25)
Clinical (21)
Methylation profiling (8)
Metabolomics (8)
Genomic (6)

Organisms

Homo sapiens (1518)
Mus musculus (487)
Drosophila melanogaster (26)
Rattus norvegicus (21)
Gallus gallus (14)
Arabidopsis thaliana (13)
Saccharomyces cerevisiae (8)
Heterocephalus glaber (7)
Sus scrofa (6)
Danio rerio (6)
Caenorhabditis elegans (5)
Bos taurus (4)
Erwinia amylovora (3)
Triticum aestivum (3)
Canis lupus familiaris (3)
Manihot esculenta (2)
Capra hircus (2)
Macaca mulatta (2)
Pan paniscus (2)
Fragilariopsis cylindrus (2)
Aspergillus fumigatus (2)
Apis mellifera (2)
Zea mays (2)
Helicobacter pylori (2)
mixed sample (2)
Saccharomyces cerevisiae S288C (2)
Salmonella enterica subsp. enterica serovar Typhimurium (2)
Mesocricetus auratus (2)
Pseudomonas aeruginosa PAO1 (2)
Plasmodium falciparum (2)

Organisms

Homo sapiens (390)
Mus musculus (104)
human lung metagenome (3)
Canis lupus familiaris (3)
unidentified (2)
Rattus norvegicus (2)
human metagenome (2)
metagenomes (1)
Mus musculus musculus (1)
human feces metagenome (1)

Repository

biostudies-arrayexpress (1726)
ENA (593)
geo (360)
pride (207)
EGA (69)
jPOST (30)
MassIVE (28)
iProX (14)
MetaboLights (7)
ExpressionAtlas (6)
dbGaP (6)
GPMDB (3)
EVA (2)
GNPS (1)
PeptideAtlas (1)

Tissue

Lung (88)
Liver (7)
Brain (6)
Lymph node (6)
Kidney (5)
Blood (4)
Bone marrow (3)
Breast (3)
Colon (3)
Pancreas (3)
Caecum (2)
Esophagus (2)
Ovary (2)
Prostate gland (2)
Stomach (2)
Testis (2)
Tongue (2)
Uterine cervix (2)
Uterus (2)
Adipose tissue (1)
Adrenal cortex (1)
Adrenal gland (1)
Amygdala (1)
Aorta (1)
Body of tongue (1)
Bone tissue (1)
Bronchus (1)
Cardia of stomach (1)
Cardiac atrium (1)
Cardiac ventricle (1)

Disease

Lung adenocarcinoma (84)
Normal (18)
Melanoma (8)
Hepatocellular carcinoma (4)
Breast adenocarcinoma (4)
Colon adenocarcinoma (3)
Glioblastoma (3)
Neuroblastoma (3)
Acute myeloid leukemia (2)
Anaplastic large cell lymphoma (2)
Breast carcinoma (2)
Breast ductal adenocarcinoma (2)
Bronchoalveolar adenocarcinoma (2)
Cecum adenocarcinoma (2)
Cervical adenocarcinoma (2)
Cervical squamous cell carcinoma (2)
Chondrosarcoma (2)
Chronic myelogenous leukemia (2)
Colon carcinoma (2)
Diffuse large B-cell lymphoma (2)
Erythroleukemia (2)
Gastric adenocarcinoma (2)
Gastric adenosquamous carcinoma (2)
Gastric carcinoma (2)
Gastric tubular adenocarcinoma (2)
Large cell lung carcinoma (2)
Lung carcinoid tumor (2)
Mesothelioma (2)
Metastatic melanoma (2)
Multiple myeloma (2)

Technology Type

Mass Spectrometry (207)
Shotgun proteomics (103)
Bottom-up proteomics (42)
Affinity purification coupled with mass spectrometry proteomics (34)
Data-dependent acquisition (28)
Data-independent acquisition (9)
SWATH MS (9)
Gel-based experiment (7)
Top-down proteomics (5)
Illumina HiSeq 2000 (4)
Mass spectrometry (4)
Mass spectrometry assay (3)
Affinity proteomics (3)
ILLUMINA, Illumina HiSeq 2000 (2)
Illumina MiSeq, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2000, ILLUMINA, Affymetrix SNP 6.0 (1)
Illumina HiSeq 2500, Illumina HiSeq 2000 (ILLUMINA), Illumina HiSeq 2000, Illumina (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
HiSeq X Ten, ILLUMINA (1)
AB 5500 Genetic Analyzer (1)
HiSeq X Ten, Illumina HiSeq 2500, ILLUMINA (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina Genome Analyzer II (1)
Olink affinity proteomics (1)
Immunopeptidomics (1)
All-ion fragmentation (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (126)
NextSeq 500 (52)
Illumina HiSeq 4000 (41)
Illumina HiSeq 2500 (32)
Illumina HiSeq 2000 (23)
NextSeq 550 (20)
Illumina NovaSeq X (18)
Illumina MiSeq (10)
Illumina HiSeq 1500 (10)
Illumina Genome Analyzer IIx (9)
NextSeq 2000 (6)
Scanning hardware (4)
DNBSEQ-G400 (4)
HiSeq X Ten (4)
PromethION (3)
ScanArray 5000 [PerkinElmer] (3)
Ion Torrent Proton (3)
N/A (3)
Novogene in-house automated library preparation system (2)
IEO HPC (2)
General usage Laborartory equipment (2)
Lab Centrifuge (2)
10x Chromium (2)
AB 5500 Genetic Analyzer (2)
Axon- GenePix4000B (2)
ScanArray 4000XL [PerkinElmer] (2)
GridION (2)
DNBSEQ-T7 (2)
BGISEQ-500 (2)
Illumina HiSeq 3000 (2)

Publication Date

2013 (212)
2014 (199)
2012 (187)
2015 (184)
2010 (166)
2016 (156)
2025 (155)
2011 (144)
2026 (132)
2021 (110)
2022 (95)
2023 (90)
2008 (89)
2024 (86)
2020 (86)
2009 (81)
2019 (61)
2018 (51)
2007 (32)
2017 (30)
2005 (15)
2006 (14)
2004 (4)
2002 (1)

UNIPROT ID/AC

Q9NQ76 (1)
P16860 (1)
Q9BXU1 (1)
Q7Z5L0 (1)
Q5BKX8 (1)
Q02747 (1)
P35247 (1)
P08476 (1)
P78509 (1)
P06734 (1)
Q9BQT9 (1)
Q96JN2 (1)
Q9HC77 (1)
P08913 (1)
P01258 (1)
Q96GE4 (1)
Q5SQN1 (1)
P08861 (1)
Q9Y240 (1)
Q7LGC8 (1)
O14498 (1)
Q08ET2 (1)
Q96FE7 (1)
Q9NQ38-3 (1)
Q9NQ38 (1)
Q9H4B8 (1)
Q9H4A9 (1)
Q96NZ9 (1)
Q96MK3 (1)
Q86UN3 (1)

ENSEMBL ID

ENSG00000229353 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:16750 (2)
CHEBI:15956 (2)
CHEBI:67016 (1)
CHEBI:178484 (1)
CHEBI:22651 (1)
CHEBI:165628 (1)
CHEBI:138519 (1)
CHEBI:177035 (1)
CHEBI:46477 (1)
CHEBI:132557 (1)
CHEBI:136665 (1)
CHEBI:50383 (1)
CHEBI:74121 (1)
CHEBI:28839 (1)
CHEBI:58562 (1)
CHEBI:138533 (1)
CHEBI:176482 (1)
CHEBI:57885 (1)
CHEBI:28490 (1)
CHEBI:17609 (1)
CHEBI:15866 (1)
CHEBI:34671 (1)
CHEBI:34146 (1)
CHEBI:133748 (1)
CHEBI:136075 (1)
CHEBI:33283 (1)
CHEBI:17502 (1)
CHEBI:27585 (1)
CHEBI:45240 (1)
CHEBI:139582 (1)

Metabolite Name

Adenine (3)
Cystathione (2)
L-cystine (2)
Lys-Gly (2)
Ile-Lys (2)
Cysteineglutathione disulfide (2)
Lithocholic acid (2)
Penicillin G (2)
Glu-Lys (2)
Kynurenine (2)
N-Acetyl-D-Glucosamine (2)
Lumichrome (2)
L-Leucine (2)
Dihydrothymine (2)
Pterine (2)
N-acetyl-l-aspartic acid (2)
L-Iditol (2)
Indole-3-carboxaldehyde (2)
Uracil (2)
Pyridoxal (2)
Phytosphingosine (2)
Oleamide (2)
N-Acetylmannosamine (2)
Hypoxanthine (2)
Hydroxyphenyllactic acid (2)
Glycerophosphocholine (2)
Cadaverine (2)
Benzoic acid (2)
L-Histidine (2)
D-Glucose (2)

First Public Date

2014 (95)
2025 (74)
2026 (61)
2023 (59)
2024 (58)
2021 (43)
2022 (40)
2020 (33)
2019 (33)
2018 (27)
2017 (23)
2015 (20)
2016 (16)
2013 (11)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study status

Recruiting (13)
Active, not recruiting (5)
Suspended (1)
Terminated (1)
Completed (1)

Study type

Transcription profiling by array (731)
RNA-seq of coding RNA (298)
Comparative genomic hybridization by array (132)
ChIP-seq (130)
RNA-seq of coding RNA from single cells (76)
RNA-seq of non coding RNA (53)
Methylation profiling by array (36)
Other (31)
Methylation profiling by high throughput sequencing (28)
RNA-seq of total RNA (18)
Unknown experiment type (17)
DNA-seq (17)
Cell line - High-throughput sequencing (15)
ChIP-chip by tiling array (13)
ChIP-chip by array (12)
Transcription profiling by RT-PCR (11)
MicroRNA profiling by array (10)
Genotyping by array (9)
ATAC-seq (9)
Animal - High-throughput sequencing (8)
Human - High-throughput sequencing (6)
Single nucleus RNA sequencing (6)
Spatial transcriptomics by high-throughput sequencing (5)
Transcription profiling by SAGE (4)
Cell line - Single-cell sequencing (3)
Animal - One-color microarray (3)
RNAi profiling by array (3)
CLIP-seq (3)
MicroRNA profiling by high throughput sequencing (3)
Hi-C (3)

Release Date

2022 (347)
2021 (335)
2016 (306)
2023 (304)
2020 (285)
2014 (281)
2015 (266)
2025 (260)
2013 (247)
2024 (242)
2012 (226)
2019 (191)
2010 (188)
2011 (187)
2018 (175)
2017 (155)
2026 (105)
2008 (96)
2009 (93)
2007 (39)
2005 (23)
2006 (14)
2004 (8)
2003 (3)
2002 (2)
2001 (2)
2000 (1)
1998 (1)

Lab affiliation

Moffitt Cancer Center Tampa, FL, USA (5)
Thoracic Oncology Moffitt Cancer Center Tampa, FL, USA (4)
Thoracic Oncology Molecular Medicine Program Moffitt Cancer Center Tampa, FL, USA (4)
Molecular Oncology Chemical Biology and Molecular Medicine Moffitt Cancer Center (3)
Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany (3)
Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (3)
1State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China 2Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, China, Peking University, Beijing 100871, China (2)
University of Colorado-Anschutz Campus (2)
Laboratory of Systems Biology, Institute of Biomedical Chemistry, Moscow (2)
Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) (2)
Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030 (2)
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. (2)
Proteomics Research Core Facility, Cancer Research UK-UCL Centre, UCL Cancer Institute, University College London,UK (2)
Chang Gung University, Taiwan (2)
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel (2)
Thoracic Oncology (2)
The Second Hospital of Dalian Medical University (2)
Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Taoyuan, Taiwan (2)
Department of Oncology Pathology, Karolinska Institute, Solna, Sweden (2)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Weizmann Institute of Science (2)
The Second Affiliated Hospital of Chengdu Medical College (China National Nuclear Corporation 416 Hospital), (1)
Harvard Medical School Beth Israel Deaconess Medical Center Director, HMS Center for Glycoscience Director, National Center for Functional Glycomics CLS 11087 - 3 Blackfan Circle Boston, MA 02115, USA (1)
Department of Oncology-Pathology, Karolinska Institutet (1)
Department of Cellular & Molecular Physiology Milton S. Hershey Medical Center Penn State College of Medicine Hershey, PA, USA (1)
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China (1)
Department of Chemistry, University of Texas at Austin, Austin (1)
Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University (1)
Thoracic and GI Malignancies Branch, CCR, NCI, NIH, Bethesda, MD (1)
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockhoom, Sweden (1)

Location

United States (18)
Germany (5)
Spain (5)
United Kingdom (4)
Belgium (4)
Netherlands (3)
France (3)
Denmark (2)
Australia (2)
Canada (2)
Italy (2)
Guam (1)
Hong Kong (1)
Norway (1)
Latvia (1)
Singapore (1)
Taiwan (1)
Lithuania (1)
Estonia (1)
Portugal (1)
Israel (1)
Sweden (1)
China (1)
Austria (1)
Japan (1)
Switzerland (1)
South Korea (1)

Keyword

Pembrolizumab (6)
Phase 1 (3)
Gemcitabine (3)
Paclitaxel (3)
Carboplatin (2)
HNSCC (2)
NRAS (2)
KRAS (2)
Nivolumab (2)
Immunotherapy (2)
Abraxane 5 mg/ml powder for suspension for infusion (1)
Cisplatin 1 mg/ml Concentrate for solution for infusion (1)
Antibody, Monoclonal (1)
IL1RAP (1)
Infusion (1)
Antineoplastic (1)
Anticancer (1)
TPST-1495 (1)
EP2 antagonist (1)
PIK3Ca mutation (1)
Farnesyl transferase inhibitor (FTI) (1)
Tyrosine Kinase inhibitor (TKI) (1)
Prostaglandin E2 (PGE2) (1)
RET Lung (1)
RET Thyroid (1)
RET fusion (1)
RET alteration (1)
RET mutation (1)
RET positive (1)
RET inhibitor (1)

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Distinct metabolic profiles in lung adenocarcinomas presenting as solid or ground-glass opacities

Metabolomic profiling provides real-time insights into tissue physiology and upstream molecular events. Despite its potential in cancer research, large-scale integrative studies in lung adenocarcinoma (LUAD) remain scarce. We analyzed 262 tissue samples from 165 LUAD patients using metabolomic, t...

2025-12-23 | MTBLS13565 | MetaboLights

Human lung adenocarcinoma tissue LC-MS/MS

This project is a report of a chromosome-based human proteome project focused on chromosome 9 (Chr 9). To reveal missing proteins and undiscovered features in proteomes, LC-MS/MS analysis based identification and characterization were conducted on 5 pairs of lung adenocarcinoma tumors and adjacent n...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079961 | MassIVE

Glycoproteomics analysis of triple wild-type lung adenocarcinoma tissue samples

Glycoproteomics analysis of triple wild-type lung adenocarcinoma tissue samples for the publication of the same name.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2024-11-18 | MSV000096450 | MassIVE

Smoking Status Impacts microRNA Mediated Prognosis and Lung Adenocarcinoma Biology

Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhibit distinct epidemiological, clinical, pathological, and molecular features depending on sm...

ORGANISM(S): Homo sapiens

2014-10-30 | E-GEOD-62182 | biostudies-arrayexpress

Human lung minimally invasive adenocarcinoma (MIA): lepidic growth (LG) cancer cell pool vs. micro-invasion (MI) cancer cell pool

Transcriptional profiling of human lung minimally invasive adenocarcinoma cells comparing control lepidic growth (LG) cell pool with micro-invasion (MI) cell pool. Two-condition experiment, LG vs. MI cell pools. Biological replicates: 1 control LG cancer cell, 1 MI cancer cell in an individual MIA t...

ORGANISM(S): Homo sapiens

2012-01-02 | E-GEOD-30663 | biostudies-arrayexpress

A blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights

Lung adenocarcinoma invasion and progression

This SuperSeries is composed of the following subset Series: GSE27675: Expression data from lung tumor and stromal cells of KrasTgfbr2 -/- mouse model GSE27716: Expression data from Columbia Lung Adenocarcinoma Human Tumor Cells GSE27717: Expression data from lung tumors of KrasTgfbr2 -/- mouse mode...

ORGANISM(S): Mus musculus

2011-09-14 | E-GEOD-27719 | biostudies-arrayexpress

Suppression of Lung Adenocarcinoma Progression by Nkx2-1

Despite the high prevalence and poor outcome of patients with metastatic lung cancer, the mechanisms of tumour progression and metastasis remain largely uncharacterized. We modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS1 and inactivation of the p53-p...

ORGANISM(S): Mus musculus

2011-01-27 | E-GEOD-26874 | biostudies-arrayexpress

Lung adenocarcinoma and mesothelioma DNA methylation

Pathologic differentiation of tissue of origin in tumors found in the lung can be challenging, with differentiation of mesothelioma and lung adenocarcinoma emblematic of this problem. Indeed, proper classification is essential for determination of treatment regimen for these diseases, making accurat...

ORGANISM(S): Homo sapiens

2010-06-25 | E-GEOD-16559 | biostudies-arrayexpress

NKX2-1 occupancy in human lung adenocarcinoma cell lines

The NKX2-1 transcription factor, a regulator of normal lung development, is the most significantly amplified gene in human lung adenocarcinoma. To better understand how genomic alterations of NKX2-1 drive tumorigenesis, we generated an expression signature associated with NKX2-1 amplification in hum...

ORGANISM(S): Homo sapiens

2013-01-22 | E-GEOD-39998 | biostudies-arrayexpress

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