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ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Secreted proteins
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-20 | PXD035987 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Cytoplasmic proteins
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-20 | PXD036017 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Proteins from nuclear extracts
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD036127 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsPrimary and hTERT-transduced mesothelioma-associated fibroblasts but not primary or hTERT-transduced mesothelial cells stimulate growth of human mesothelioma cells_Secreted proteins
Introduction: Pleural mesothelioma (PM) is known as one of the most aggressive malignancies among all cancers, despite of usually absent tumor-driver mutations in oncogenes. It develops in a unique inflammatory tumor microenvironment (TME), which has been postulated as major contributor of PM’s high...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD043511 | Pride
Htert Mesothelioma-associated fibroblasts Pleural mesothelial cells Pleural mesothelioma Conditioned medium Human telomerase reverse transcriptase Tumor microenvironment 
ProteomicsPrimary and hTERT-transduced mesothelioma-associated fibroblasts but not primary or hTERT-transduced mesothelial cells stimulate growth of human mesothelioma cells_ Cytoplasmic proteins & Proteins from nuclear extracts
Introduction: Pleural mesothelioma (PM) is known as one of the most aggressive malignancies among all cancers, despite of usually absent tumor-driver mutations in oncogenes. It develops in a unique inflammatory tumor microenvironment (TME), which has been postulated as major contributor of PM’s high...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD043534 | Pride
Htert Mesothelioma-associated fibroblasts Pleural mesothelial cells Pleural mesothelioma Conditioned medium Human telomerase reverse transcriptase Tumor microenvironment 
UnknownMesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin.
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S-EPMC9869633 | biostudies-literature
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