Sort   by:  
 Page size 
TranscriptomicsTranscriptomes of whole blood and PBMC in chickens.
The gene expression profiles of chicken whole blood (WB) and peripheral blood mononuclear cells (PBMC) have been characterized and compared by microarray analysis. This study highlights the respective advantages of each blood cell subset and show that whole blood is more suitable for large scale st...
ORGANISM(S): Gallus gallus 
2016-07-22 | E-GEOD-65331 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Peripheral Blood Mononuclear Cells Exposed to Lassa Virus and to the Reassortant ML29, a Vaccine Candidate
The virulent Lassa fever virus (LASV) and the non-pathogenic Mopeia virus (MOPV) infect rodents and incidentally people in West Africa. The mechanism of LASV damage in human beings is unclear. A live-attenuated reassortant of MOPV and LASV protects rodents and primates from Lassa fever disease. Peri...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-41300 | biostudies-arrayexpress
TranscriptomicsExpression profiles of PBMC from multiple sclerosis patients
Affymetrix GeneChip Human Gene 1.0 ST Array was applied to compare the expression profiles in peripheral blood mononuclear cells(PBMC) between healthy controls and multiple sclerosis patients(MS pt). It suggested that certain genes involved in apoptosis pathway have been changed regulated in PBMC ...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-23832 | biostudies-arrayexpress
TranscriptomicsComparison of CD8+ memory T-cells from fresh and high density precultured PBMC.
High density cultured CD8+ memory T-cells from peripheral blood mononuclear cells (PBMC) were found to be more sensitive towards antigenic stimulation. We used microarrays to detail the global programme of gene expression underlying differences in the cell density of human PBMC and identified genes ...
ORGANISM(S): Homo sapiens 
2015-06-09 | E-GEOD-63430 | biostudies-arrayexpress
TranscriptomicsExpression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence
Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gene expression profiles leading to development of different diseases and disorders are not fully understood. The knowledge of global gene expression will help us to develop early disease or disorder bio...
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-22668 | biostudies-arrayexpress
TranscriptomicsExpression data from human CD4 or CD8 T-cells isolated from PBMC cultured at a low cell density (LDC) or high cell density (HDC)
Research in human immunobiology is mainly based on working with peripheral blood mononuclear cells (PBMC). However, recent investigations have shown that circulating CD4+ T cells are less sensitive to several T-cell activating monoclonal antibodies (mAb) and to recall antigens as compared to tissue-...
ORGANISM(S): Homo sapiens 
2015-06-09 | E-GEOD-51288 | biostudies-arrayexpress
TranscriptomicsH2O2 Treatment of Human PBMC
To mimic the effect of ROS in contributing to ageing process in immune cells of PBMC. The PBMC cells were harvested from old human subjects (>50) and induced with H2O2 during 3 hour and 6 hour. The CEL file were normalized using RMA methods. We used microarray to explore the gene expression profilin...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22463 | biostudies-arrayexpress
TranscriptomicsImmune cell subsets and their gene expression profiles from human PBMC isolated by Vacutainer Cell Preparation Tube and standard density gradient
High quality genetic material is an essential pre-requisite when analyzing gene expression using microarray technology. Peripheral blood mononuclear cells (PBMC) are frequently used for genomic analyses, but several factors can affect the integrity of nucleic acids prior to their extraction, includi...
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-67321 | biostudies-arrayexpress
MetabolomicsDiverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood
During human fasting, metabolic markers, including butyrates, carnitines, and branched-chain amino acids, are upregulated for energy substitution through gluconeogenesis and use of stored lipids. We performed non-targeted, accurate semiquantitative metabolomic analysis of human whole blood, plasma, ...
2019-09-11 | MTBLS549 | MetaboLights
TranscriptomicsChanges in PBMC gene expression profiles after influenza vaccination in healthy human subjects
Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. Temporal patterns of gene expression, determined by RNA-seq, in unfractionated PBMC suggested migration of myeloid/dendritic cell lineage cells o...
ORGANISM(S): Homo sapiens 
2013-08-07 | E-GEOD-45735 | biostudies-arrayexpress
Sort   by:  
 Page size