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Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes
Regulated intracellular proteolysis is essential in maintaining the integrity of podocytes and the glomerular filtration barrier of the kidney. Altered proteolytic substrate turnover has been associated with various glomerular diseases ranging from diabetic nephropathy to focal and segmental glomeru...
ORGANISM(S): Homo sapiens (Human) 
2017-07-20 | PXD005140 | Pride
Purpose: Next-generation sequencing (NGS) was used to identify cellular pathways and genes through systems-based analysis. The goals of this study are to identify NGS-derived transcriptome profiling (RNA-seq) in control (untreated) and Injured (PAN and Adriamycin) podocyte. These high throughput dat...
ORGANISM(S): Homo sapiens 
2019-03-31 | GSE124622 | GEO
Podocytes are terminally differentiated cells at the kidney filtration barrier and exposed to considerable mechanical strain. Podocyte injury causes morphological changes as a result of cytoskeletal reorganizations and failure of the filtration barrier. The transcriptional co-activators YAP/TAZ are ...
ORGANISM(S): Homo sapiens (Human) 
2017-04-19 | PXD003872 | Pride
RNA-seq of podocytes treated with glomerular endothelial cell vesicles
sRNA-seq of podocytes treated with glomerular endothelial cell vesicles
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