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MetabolomicsSelective galactose culture condition reveals distinct metabolic signatures in pyruvate dehydrogenase and complex I deficient human skin fibroblasts

INTRODUCTION: A decline in mitochondrial function represents a key factor of a large number of inborn errors of metabolism, which lead to an extremely heterogeneous group of disorders.

OBJECTIVES: To gain insight into the biochemical consequences of mitocho...

2021-10-06 | MTBLS761 | MetaboLights
MetabolomicsLC-MS untargeted lipidomics of primary human fibroblasts
Not available
ORGANISM(S): Homo sapiens 
ST001691 | MetabolomicsWorkbench
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with IL1-beta
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079966 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079940 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with TGF-beta
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079968 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-distant tissue sections
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079950 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - ZR-75-1 breast cancer cells
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079958 | MassIVE
ProteomicsPrimary human cardiac ventricular fibroblasts
Transformed AC16 cells were acquired from Millipore and used at P10-15 and expanded in DMEM/F-12 with 10% FBS (Gibco). Primary human ventricular cardiac fibroblasts were acquired from Promocell and expanded in FGM-3 (Promocell) and used at P3-5. For the experiment, cells were separately placed on tr...
ORGANISM(S): Homo Sapiens (human) 
2023-05-05 | PXD041982 | JPOST Repository
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - bulk tumor tissue
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079947 | MassIVE
ProteomicsProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-near tissue sections
Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079953 | MassIVE
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