Human proteome map

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Proteomics (892)
Unknown (327)
Transcriptomics (44)
Models (32)
Genomics (31)
Metabolomics (12)
Multiomics (6)
Other (4)
Methylation profiling (1)

Organisms

Allexis (661)
Arabidopsis thaliana (661)
Entamoeba histolytica HM-1:IMSS-A (661)
Escherichia coli (661)
Homo sapiens (661)
Listeria monocytogenes (661)
Medicago truncatula (661)
Meleagris gallopavo (661)
Methylohalobius crimeensis 10Ki (661)
Mus musculus (661)
Rattus norvegicus (661)
Saccharomyces cerevisiae (661)
Schizosaccharomyces pombe (661)
Sinorhizobium meliloti BL225C (661)
Solanum tuberosum (661)
Homo sapiens (176)
Fusarium sinicum (27)
Mus musculus (9)
Caenorhabditis elegans (2)
Rattus norvegicus (2)
Thalassiosira pseudonana CCMP1335 (1)
Bartonella henselae (1)
Burkholderia cenocepacia (1)
Saccharomyces cerevisiae (1)
Drosophila melanogaster (1)
Human coronavirus OC43 (1)
108887 (1)
Arabidopsis thaliana (1)
Rattus rattus (1)
Labeo rohita (1)

Organisms

Homo sapiens (18)
Mus musculus (3)

Repository

pride (661)
PeptideAtlas (72)
MassIVE (63)
PAXDB (50)
BioModels (32)
biostudies-arrayexpress (30)
ENA (26)
jPOST (22)
geo (20)
iProX (17)
MetaboLights (11)
PanoramaPublic (5)
GPMDB (3)
EGA (2)
ExpressionAtlas (1)
GNPS (1)

Tissue

Cell culture (181)
Blood (69)
Others (54)
Brain (48)
Epithelial cell (36)
Permanent cell line cell (29)
T cell (29)
Lung (27)
B cell (25)
Blood plasma (25)
Liver (20)
Heart (19)
Kidney (17)
HeLa cell (16)
Colon (15)
Skin (14)
Bone marrow (12)
Melanocyte (12)
Monocyte (12)
Spleen (12)
Plasma Non-glyco (11)
Fibroblast (11)
Macrophage (11)
Cell suspension culture (9)
Hepatocyte (8)
Neutrophil (8)
Ovary (8)
Placenta (8)
Stem cell (8)
Urine (1)

Disease

Disease free (79)
Melanoma (13)
Colon cancer (11)
Alzheimer's disease (10)
Breast cancer (10)
Lymphoma (8)
Cervix carcinoma (6)
Acute leukemia (5)
Brain cancer (4)
COVID-19 (4)
Lung cancer (4)
Pancreatic ductal adenocarcinoma (4)
Prostate adenocarcinoma (4)
Not Available (3)
Amyotrophic lateral sclerosis (3)
Bacterial sepsis (3)
Glioblastoma (3)
Lung adenocarcinoma (3)
Parkinson's disease (3)
Schizophrenia (3)
Normal (2)
Acute myeloid leukemia (2)
Amelanotic melanoma (2)
Cardiovascular system disease (2)
Cell type cancer (2)
Cystic fibrosis (2)
Malignant neoplasm of ovary (2)
Clear cell renal cell carcinoma (1)
Papillary renal cell carcinoma (1)
Chromophobe renal cell carcinoma (1)

Technology Type

Mass Spectrometry (661)
Shotgun proteomics (364)
Bottom-up proteomics (115)
Data-dependent acquisition (71)
Affinity purification coupled with mass spectrometry proteomics (69)
Top-down proteomics (67)
Data-independent acquisition (29)
Gel-based experiment (29)
SWATH MS (18)
Chemical cross-linking coupled with mass spectrometry proteomics (12)
SRM/MRM (10)
Mass spectrometry (9)
Affinity proteomics (3)
DiaPASEF (3)
HDMSE (3)
Immunopeptidomics (3)
MSE (3)
All-ion fragmentation (2)
Glycoproteomics (2)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Mass spectrometry imaging (1)
Metaproteomics (1)
Olink affinity proteomics (1)
Proteogenomics (1)
Two Dimensional Polyacrylamide Gel Electrophoresis (1)

Instrument Platform

LTQ Orbitrap Velos (32)
LTQ Orbitrap Elite (22)
TripleTOF 5600 (17)
Q Exactive (14)
LTQ (9)
Q Exactive HF (6)
LTQ Orbitrap (5)
Orbitrap Fusion (5)
Orbitrap Fusion Lumos (5)
Illumina HiSeq 2500 (3)
Instrument (3)
MS:1000044 (3)
MS:1000419 (3)
Orbitrap Exploris 480 (3)
Q Exactive HF-X (3)
Q Exactive Plus (3)
Illumina MiSeq (2)
MS:1000031 (2)
Orbitrap Astral (2)
TimsTOF (2)
Coulter Automated Workstation Biomek i7 Hybrid (1)
RNeasy 96-well plate kit (1)
None (1)
Illumina HiSeq X (1)
NextSeq 2000 (1)
Illumina HiSeq 1500 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 2000 (1)
6520A Quadrupole Time-of-Flight LC/MS (1)
Bruker Daltonics instrument model (1)

Publication Date

2022 (138)
2015 (97)
2024 (92)
2025 (92)
2020 (87)
2021 (79)
2023 (71)
2026 (69)
2014 (54)
2019 (48)
2018 (45)
2017 (38)
2016 (31)
2013 (13)
2008 (8)
2012 (5)
2011 (4)
2010 (2)
2007 (2)

UNIPROT ID/AC

1433S_HUMAN (27)
A1AG1_HUMAN (27)
A1AG2_HUMAN (27)
A1BG_HUMAN (27)
A2AP_HUMAN (27)
A2GL_HUMAN (27)
A2MG_HUMAN (27)
ACTG_HUMAN (27)
AFAM_HUMAN (27)
AMBP_HUMAN (27)
AMPN_HUMAN (27)
ANGT_HUMAN (27)
ANT3_HUMAN (27)
APMAP_HUMAN (27)
APOA1_HUMAN (27)
APOA2_HUMAN (27)
APOA4_HUMAN (27)
APOB_HUMAN (27)
APOC1_HUMAN (27)
APOC3_HUMAN (27)
APOD_HUMAN (27)
APOE_HUMAN (27)
APOF_HUMAN (27)
APOH_HUMAN (27)
APOL1_HUMAN (27)
AT1A1_HUMAN (27)
ATRN_HUMAN (27)
BGH3_HUMAN (27)
BLVRB_HUMAN (27)
BTD_HUMAN (27)

ENSEMBL ID

ENSG00000170477 (62)
ENSG00000147251 (27)
ENSG00000247315 (13)
ENSG00000204131 (4)
ENSG00000229353 (1)

CHEBI ID

CHEBI:3110 (32)
CHEBI:16874 (32)
CHEBI:16565 (32)
CHEBI:27515 (32)
CHEBI:36528 (32)
CHEBI:15958 (32)
CHEBI:17927 (32)
CHEBI:28101 (32)
CHEBI:28865 (32)
CHEBI:17687 (32)
CHEBI:36274 (32)
CHEBI:16675 (32)
CHEBI:28058 (32)
CHEBI:17292 (32)
CHEBI:16091 (32)
CHEBI:28648 (32)
CHEBI:28175 (32)
CHEBI:18163 (32)
CHEBI:17798 (32)
CHEBI:17364 (32)
CHEBI:17474 (32)
CHEBI:27870 (32)
CHEBI:27910 (32)
CHEBI:17500 (32)
CHEBI:17737 (32)
CHEBI:15700 (32)
CHEBI:17123 (32)
CHEBI:17864 (32)
CHEBI:16797 (32)
CHEBI:16427 (32)

Metabolite Name

Leucine (3)
Olomoucine (3)
Tris(hydroxymethyl)aminomethane (3)
Valine (3)
Glutathione (3)
Sphingosine 1-phosphate (3)
Triethanolamine (3)
Phytosphingosine (3)
Benzoic acid (3)
Choline (3)
Taurine (3)
Docosahexaenoic acid (3)
Arginine (3)
Proline (3)
Phenylalanine (3)
Isoleucine (3)
Creatine (3)
(-)-Rhododendrin (2)
(2E)-2-Tridecene-4,6,8-triyn-1-ol (2)
(2E,4E,12Z)-N-Isobutyl-2,4,12-octadecatrienamide (2)
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(2-phenylethoxy)oxane-3,4,5-triol (2)
(2R,3S,4S,5S,6R)-2-({7-hydroxy-4-[(3Z)-5-hydroxy-3-methylpent-3-en-1-yl]-4a,8,8-trimethyl-3-methylidene-decahydronaphthalen-2-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol (2)
(2S)-2-Amino-8-hydroxyoctanoic acid (2)
(4E)-1,7-Bis(4-hydroxyphenyl)-4-hepten-3-one (2)
(9Z)-9-Octadecenamide (2)
(E)-Dacarbazine (2)
(E)-p-coumaric acid (2)
(Z)-3-butylidene-7-hydroxyphthalide (2)
[(4Z)-5-(Methylsulfanyl)-4-penten-2-yn-1-yl]benzene (2)
1,2-Cyclohexadione (2)

First Public Date

2020 (6)
2021 (4)
2024 (3)
2026 (2)
2025 (2)
2023 (2)
2018 (2)
2017 (2)
2013 (2)
2022 (1)

Lab affiliation

Departments of Chemical and Biological Engineering, Chemistry, and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States (55)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (24)
Merck (6)
Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (5)
Proteomics - Bioinformatics (5)
Distinguished Professor Associate Chair for Undergraduate Affairs (4)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (4)
BGI Research (3)
Cellzome, a GSK company (3)
Department of Chemistry and Chemical Biology, Harvard University (3)
Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA (3)
Department of Neurobiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (3)
European Molecular Biology Laboratory (EMBL), Genome Biology Unit (3)
Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. (3)
Lineberger Comprehensive Cancer Center at UNC Chapel Hill (3)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USA (3)
Moffitt Cancer Center Tampa, FL, USA (3)
The Scripps Research Institute (3)
BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea (2)
Chair, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA (2)
College of Chemistry and Molecular Engineering, Peking University, Beijing, China. (2)
Department of Chemistry and Biochemistry. University of Colorado, Boulder. Boulder, CO 80303 (2)
Department of Chemistry, Imperial College London, Molecular Research Science Hub, 80 Wood Lane, London W12 0BZ, United Kingdom. The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom. (2)
Department of Modeling of Biological Processes COS, Heidelberg University (2)
Department of Molecular and Applied Microbiology Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Germany (2)
Department of Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) (2)
Emmy-Noether Research Group Cellular Proteomics and Metabolic Signaling Institute for Diabetes and Obesity Helmholtz Diabetes Center Germany (2)
Faculty of Chemistry, Biotechnology and Food Science Norwegian University of Life Sciences Post Office Box 5003 1432, Ås Norway (2)
Functional Proteomics, ICR (2)
Harvard Medical School (2)

IsPrivate

False (32)

Model Flag

Non Kinetic (32)

Modification

-17.026549 (2)
15.994915 (2)
42.010565 (2)
57.021464 (2)
N6 (2)
N6-dimethyl-L-lysine (2)
-18.010565 (1)
71.037114 (1)

Study type

Transcription profiling by array (13)
RNA-seq of coding RNA (12)
Transcription profiling by SAGE (1)
RNA-seq of non coding RNA from single cells (1)
Proteomic profiling by mass spectrometer (1)
Antigen profiling (1)
DNA-seq (1)

Release Date

2024 (42)
2021 (37)
2022 (26)
2023 (25)
2017 (24)
2020 (23)
2015 (21)
2019 (21)
2025 (20)
2018 (19)
2016 (16)
2014 (14)
2011 (14)
2013 (9)
2026 (8)
2012 (7)
2010 (6)
2008 (6)
2007 (6)
2009 (3)
2006 (3)
2004 (3)
2003 (2)
2005 (1)
1999 (1)

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Thermal Profiling Maps Multilayered Organization of the Mitochondrial Proteome

Mitochondria execute essential metabolic, biosynthetic, and signaling functions, yet the regulatory principles governing their proteome remain incompletely understood. Here, we develop a thermal proteome profiling (TPP) workflow applied directly to purified mitochondria, enabling systematic analy...

2025-12-08 | MTBLS7386 | MetaboLights

Reanalysis of Pandey lab's draft of the human proteome

The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides was lacking. To this end, Akhilesh Pandey's lab reported a draft map of the human proteome based on...

ORGANISM(S): Homo sapiens

2015-03-10 | E-PROT-1 | biostudies-arrayexpress

Uhlén2015 - Human tissue-based proteome metabolic network - stomach

Uhlén2015 - Human tissue-based proteome metabolic network - stomach Human stomach specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, S...

2015-01-28 | MODEL1411240017 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - adipose

Uhlén2015 - Human tissue-based proteome metabolic network - adipose Human adipose tissue specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinog...

2015-01-28 | MODEL1411240001 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - skeletal

Uhlén2015 - Human tissue-based proteome metabolic network - skeletal Human skeletal tissue specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardin...

2015-01-28 | MODEL1411240009 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - testis

Uhlén2015 - Human tissue-based proteome metabolic network - testis Human testis specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siv...

2015-01-28 | MODEL1411240018 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - adrenal

Uhlén2015 - Human tissue-based proteome metabolic network - adrenal Human adrenal specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, S...

2015-01-28 | MODEL1411240002 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - endometrium

Uhlén2015 - Human tissue-based proteome metabolic network - endometrium Human endometrium specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardino...

2015-01-28 | MODEL1411240010 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - appendix

Uhlén2015 - Human tissue-based proteome metabolic network - apendix Human apendix specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, S...

2015-01-28 | MODEL1411240004 | BioModels

Uhlén2015 - Human tissue-based proteome metabolic network - kidney

Uhlén2015 - Human tissue-based proteome metabolic network - kidney Human kidney specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siv...

2015-01-28 | MODEL1411240019 | BioModels

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