Human somitoids

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RNA-seq of coding RNA from single cells (1)

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2022 (4)
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Lab affiliation

Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands (3)
Department of Urology, Radboud Institute for Medical Innovation, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands. (1)
Radboud Universiteit Nijmegen NL (1)

Tags

xref:PubMed:36245268 (3)
xref:PubMed:42634066 (3)
xref:PubMed:36543321 (1)
xref:PubMed:35088712 (1)
xref:PubMed:38754429 (1)

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scRNA-seq of human somitoids that periodically form somite-like structures

Single-cell RNA sequencing (10X) analyses of human somitoids, novel organoids that periodically form somite-like structures from human iPS cells. Somitoids made with and without Matrigel were compared. Somitoids treated with different concentrations of CHIR (WNT signaling activator) during the initi...

ORGANISM(S): Homo sapiens

2022-04-07 | E-MTAB-11334 | biostudies-arrayexpress

P300 proximity labeling in human somitoids

This dataset presents the results of proximity-dependent biotinylation targeting the transcriptional coactivator p300 in human somitoids. We endogenously tagged p300 with the biotin ligase miniTurboID in iPSCs, to enable labeling of proximal proteins and thus proteins locatd at enhancers. hiPSCs wer...

ORGANISM(S): Homo sapiens (Human)

2026-08-07 | PXD070251 | Pride

scRNA-seq of human somitoids that periodically form somite-like structures

PRJEB49868 | ENA

From stem cells to somites: revealing genetic and exogenous factors of human embryogenesis

In this project, we characterized the temporal dynamics of protein expression during the differentiation of human iPSCs to somitoids, stem cell–derived 3D models that recapitulate early embryonic somitogenesis. Using quantitative time-course proteomics, we captured how protein abundance changed as p...

ORGANISM(S): Homo sapiens (Human)

2026-08-07 | PXD079129 | Pride