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TranscriptomicsTranscription profiling by array for comparison of industrial Escherichia coli strains on growth, transcriptome and proteome level in batch cultivations to identify strain specific features (subexperiment K-12 platform)
The objective of the current study was to evaluate the performance of frequently used E. coli K-12 strains HMS174 and RV308 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied tran...
ORGANISM(S): Escherichia coli 
2013-08-19 | E-MARS-20 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array for comparison of industrial Escherichia coli strains on growth, transcriptome and proteome level in batch cultivations to identify strain specific features (subexperiment BL21 platform)
The objective of the current study was to evaluate the performance of frequently used E. coli BL21 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied transcriptome analysis to int...
ORGANISM(S): Escherichia coli 
2013-08-19 | E-MARS-21 | biostudies-arrayexpress
TranscriptomicsHistone acetylation and DNA demethylation of T-cells result in an anaplastic large cell lymphoma-like phenotype.
A characteristic feature of anaplastic large cell lymphoma (ALCL) is the significant reduction of the T-cell expression program despite its T-cell origin, a finding very similar to the loss of B-cell identity of classical Hodgkin lymphoma (cHL). Previously we demonstrated that epigenetic mechanisms ...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-26101 | biostudies-arrayexpress
TranscriptomicsClassical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of PCM vs. B-cell lines
Background Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkin lymphoma. However, little is known regarding epigenetic similarities between classical Hodgkin lymphoma and plasma cell myeloma cells, both of which share an extinction of the gene...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-28079 | biostudies-arrayexpress
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