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UnknownGenetic history of hepatitis C virus in East Asia.
Not available
S-EPMC2612398 | biostudies-literature
UnknownInterplay of host and viral genetic variations in modulating antibody responses to genotype 3a hepatitis C virus: Implications for vaccine design.
Not available
S-EPMC7618651 | biostudies-literature
UnknownCXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver.
Not available
S-EPMC3994510 | biostudies-literature
MetabolomicsPaternal microbiome perturbations impact offspring fitness

The gut microbiota operates at the interface of host-environment interactions to influence human homeostasis and metabolic networks. Environmental factors that unbalance gut microbial ecosystems can therefore elicit physiological and disease-associated responses across somatic tissues. However, t...

2024-02-12 | MTBLS1629 | MetaboLights
TranscriptomicsRNA-seq profiling of MED patient-derived (MATN3 V194D) and unaffected iPSC-chondrogenesis
PBMCs from MED patients carrying the MATN3 V194D mutation and unaffected controls were reprogrammed into hiPSCs. Samples were differentiated into Day 21 cartilage pellets via an iMSC intermediate.
ORGANISM(S): Homo sapiens 
2026-02-12 | E-MTAB-16600 | biostudies-arrayexpress
TranscriptomicsTranscriptomic time-series of human embryonic stem cell differentiation to hypertrophic-like chondrocytes via a mesenchymal intermediate
This study characterizes the gene expression changes during the differentiation of the human embryonic stem cell (hESC) line Man13 into hypertrophic-like cartilage pellets. Samples include five key stages: pluripotent cells (TeSR™-E8™), induced mesenchymal stromal cells (iMSCs), and three-dimensiona...
ORGANISM(S): Homo sapiens 
2026-02-12 | E-MTAB-16597 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of MED patient-derived (MATN3 T195K) and unaffected iPSC-chondrogenesis
PBMCs from MED patients carrying the MATN3 T195K mutation and unaffected controls were reprogrammed into hiPSCs using Sendai virus. Data includes three differentiation stages: pluripotent hiPSCs, iMSCs, and Day 21 cartilage pellets. Sequencing was performed at the University Genomics Core Facility.
ORGANISM(S): Homo sapiens 
2026-02-12 | E-MTAB-16598 | biostudies-arrayexpress
TranscriptomicsGene expression profile of control and CRISPR-edited MATN3 V194D mutant Day 21 cartilage pellets differentiated from the human ESC line MAN13
RNA-seq of control and MATN3 V194D mutant cartilage pellets. The MATN3 V194D mutation was introduced using CRISPR-Cas9 in pluripotent cells before differentiation through an iMSC intermediate to Day 21 cartilage pellets.
ORGANISM(S): Homo sapiens 
2026-02-12 | E-MTAB-16599 | biostudies-arrayexpress
GenomicsGEUTFIN
GenomEUtwin Finnish (FIN) samples
EGAD00000000042 | EGA
GenomicsH3
NcOEDG Helsinki 3 samples
EGAD00000000034 | EGA
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