This a model from the article:
Rate dependence and regulation of action potential and calcium transient in a
canine cardiac ventricular cell model.
Hund TJ, Rudy Y. Circulation
2004 Nov 16;110(20):3168-74 15505083
,
Abstrac...
Fibrosis is a pronounced feature of heart disease and the result of dysregulated activation of resident cardiac fibroblasts (CFs). Recent work identified stress-induced degradation of the cytoskeletal protein βIV-spectrin as an important step in CF activation and cardiac fibrosis. Further, loss of β...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Chlorocebus sabaeus