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TranscriptomicsNOD2-dependent licensing of the microbiota predispose to transmissible inflammation and tumorigenesis in the colon.
Instability in the composition of gut bacterial communities, referred as dysbiosis, has been associated with important human intestinal disorders such as CrohnM-bM-^@M-^Ys disease and colorectal cancer. Here, we show that dysbiosis coupled to Nod2 or Rip2 deficiency suffices to cause an increased ri...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-32421 | biostudies-arrayexpress
TranscriptomicsNOD2 transmissible microbiota predispose WT mice to inflammation
Instability in the composition of gut bacterial communities, referred as dysbiosis, has been associated with important human intestinal disorders such as Crohn’s disease and colorectal cancer. Our data showed that Nod2-mediated risk of intestinal inflammation in colitis model is communicable to WT m...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-36481 | biostudies-arrayexpress
TranscriptomicsThe multifaceted RisA regulon of Bordetella pertussis
Bordetella pertussis, the etiological agent of whooping cough, regulates the expression of its virulence factors by the well-defined BvgA/S two-component regulatory system. Phosphorylated BvgA activates the virulence activated genes (vags) and represses via the activation of the bvgR gene the expres...
ORGANISM(S): Bordetella pertussis 
2016-08-20 | E-GEOD-77754 | biostudies-arrayexpress
TranscriptomicsThe Nlrp12 inflammasome negatively regulates NOD2-mediated adjuvanticity, endotoxic shock and host defence afforded by an immunomodulatory muropeptide.
Transcriptional profiling of intestinal response to Citrobacter rodentium in wild-type and Nlrp12-deficient mice Four-conditions experiment, Nlrp12-deficient mouse infected by Citrobacter rodentium at day 7 versus non-infected Nlrp12-deficient mice with two biologicals replicates , Wild-type mouse i...
ORGANISM(S): Mus musculus 
2015-07-25 | E-GEOD-59940 | biostudies-arrayexpress
TranscriptomicsDifferential expression of certain genes during somatic embryogenesis in leaf explants of Cichorium intybus
In Cichorium intybus, macroscopic and histological modifications were identified during in vitro cell reactivation and morphogenesis events. The relationships between these modifications and transcript profiles of genes were investigated. Two chicory genotypes derived from the Hungarian landrace Koo...
ORGANISM(S): Cichorium intybus 
2010-06-20 | E-GEOD-15502 | biostudies-arrayexpress
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