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ProteomicsComplexome profiling of subcellular fractions of Plasmodium falciparum gametocytes
The aim of the experiment was to get a better understanding of the complexome of Plasmodium falciparum gametocytes and its subcellular distribution. To do so we, whole parasite cells were isolated and subjected to nitrogen cavitation to free cellular content and homogenize the sample. To decrease sa...
ORGANISM(S): Plasmodium falciparum 
2024-10-17 | PXD050751 | Pride
Lc-msms Complexome profiling Plasmodium falciparum 
TranscriptomicsTranscriptomes of monocyte-derives DCs stimulated with various compounds
Little is known about the early transcriptional events in innate immune signaling in immature and tolerogenic monocyte-derived dendritic cells (DCs), the professional antigen-presenting cells of our immune system. TLR ligands usually induce a proinflammatory transcriptional response, whereas IL10 an...
ORGANISM(S): Homo sapiens 
2011-07-08 | E-GEOD-23371 | biostudies-arrayexpress
GenomicsDNA sequencing of selected Globobulimina pseudospinescens organisms
We introduce FACIL (http://www.cmbi.ru.nl/FACIL), a fast, reliable tool to evaluate nucleic acid sequences for non-standard codes that detects alternative genetic codes even in species distantly related to known organisms. Results are visualized in a Genetic Code Logo. To illustrate the use of our m...
ORGANISM(S): Globobulimina pseudospinescens 
2011-06-20 | E-GEOD-26664 | biostudies-arrayexpress
UnknownComprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing.
Not available
S-EPMC3710099 | biostudies-literature
GenomicsGenome-wide profiling of p63 binding sites identifies genes and regulatory elements for p63-related disorders
We identified p63 target genes and binding sites responsible for ectodermal defects by genome-wide profiling of p63 binding using ChIP-seq and expression analysis in human primary keratinocytes from patients with p63 mutations. As proof of principle, we identified a novel de novo microdeletion causi...
ORGANISM(S): Homo sapiens 
2010-08-15 | E-GEOD-17611 | biostudies-arrayexpress
GenomicsChromatin accessibility, p300 and histone acetylation define PML-RARalpha- and AML1-ETO-binding sites
Chromatin accessibility is a key determinant of cell-type-specific gene expression. Here, we have investigated the chromatin architecture of different acute myeloid leukemia (AML) cells and the changes in accessibility when NB4 (APL) cells undergo the process of differentiation. For nuclease-accessi...
ORGANISM(S): Homo sapiens 
2012-08-29 | E-GEOD-30254 | biostudies-arrayexpress
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