We used microarrays to assess transcriptional changes in regulatory T cells upon deletion of PTEN. Foxp3+ CD25+ or Foxp3+ CD25- cells were double-sorted from 3 individual healthy 7 week old mice to over 99% purity.
Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an accessible and inexpensive therapeutic intervention that can improve mitochondrial bioenergetics and quality of life. By combining a multi-omics approach with biochemical and in silico normalisation, we remo...
