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ProteomicsProteome resource allocation in bacteria
A central aim of cell biology is to understand the strategy of gene expression in response to the environment. Here we study gene expression response to metabolic challenges in exponentially growing Escherichia coli using mass spectrometry. Despite enormous complexity in the details of the underlyin...
ORGANISM(S): Escherichia coli 
2015-02-12 | PXD001467 | Pride
Escherichia coli Proteome partition Growth physiology 
ProteomicsGlobal coordination of metabolic pathways in Escherichia coli by active and passive regulation
In this study, we identify the regulatory mechanisms that coordinate catabolism and anabolism in the bacterium Escherichia coli. Integrating protein, metabolite, and metabolic flux changes in genetically implemented gradual catabolic or anabolic limitations, we show that a combination of global and ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2021-03-03 | MSV000086992 | MassIVE
UnknownSuboptimal resource allocation in changing environments constrains response and growth in bacteria
Not available
S-SCDT-MSB-2021-10597 | biostudies-other
ProteomicsFrom coarse to fine: The absolute Escherichia coli proteome under diverse growth conditions
Accurate measurements of cellular protein concentrations are invaluable to quantitative studies of gene expression and physiology in living cells. Here, we developed a versatile mass spectrometric workflow based on data-independent acquisition proteomics (DIA/SWATH) together with a novel protein inf...
ORGANISM(S): Escherichia Coli 
2022-01-12 | PXD017258 | panorama
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