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ProteomicsLiver Proteomics of the Hybrid Mouse Diversity Panel
Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease. Unfortunately, our understanding of the contributing pathways that initiate and advance hepatosteatosis to subsequent complications is still poorly understood. Here, we take advantage of r...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-05 | PXD010818 | Pride
Liver Hybrid mouse diversity panel 
TranscriptomicsBone microarray profiles from the Hybrid Mouse Diversity Panel
Significant advances have been made in the discovery of genes affecting bone mineral density (BMD); however, our understanding of its genetic basis remains incomplete. In the current study, genome-wide association (GWA) and co-expression network analysis was used in the recently described Hybrid Mo...
ORGANISM(S): Mus musculus 
2011-02-25 | E-GEOD-27483 | biostudies-arrayexpress
TranscriptomicsHybrid Mouse diversity Panel Liver Expression Profile
Novel, systems-based approach to mouse genetics. Expression Profiles from 99 strains of inbred and recombinant inbred mice. Most assayed in triplicate. Two of 288 chips were excluded from the final analysis due to low QC scores.
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-16780 | biostudies-arrayexpress
ProteomicsProteomic analysis of skeletal muscle from the Hybryid Mouse Diversity Panel
To begin to understand how variations in the genome drive changes in the skeletal muscle proteome, we performed a proteomic analysis of Gastrocnemius muscle from 73 inbred mouse strains of the Hybrid Mouse Diversity Panel (HMDP) that were fed a chow diet and housed under identical environmental cond...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-08 | PXD032729 | Pride
Hybrid mouse diversity panel Skeletal muscle 
TranscriptomicsTranscriptomes of the hybrid mouse diversity panel subjected to Isoproterenol challenge
Transcriptomes performed on left ventricular heart samples from mice of the hybrid mouse diversity panel, a set of over a hundred inbred strains of mice. In this project, the strains were challenged with Isoproterenol, a beta-adrenergic agonist to induce cardiac hypertrophy and failure. Results ar...
ORGANISM(S): Mus musculus 
2013-07-10 | E-GEOD-48760 | biostudies-arrayexpress
TranscriptomicsTranscriptomes of the hybrid mouse diversity panel subjected to Isoproterenol challenge
Transcriptomes performed on left ventricular heart samples from mice of the hybrid mouse diversity panel, a set of over a hundred inbred strains of mice. In this project, the strains were challenged with Isoproterenol, a beta-adrenergic agonist to induce cardiac hypertrophy and failure. Results are ...
ORGANISM(S): Mus musculus 
2013-07-10 | GSE48760 | GEO
TranscriptomicsLiver expression data from 31 mouse strains treated with vehicle or isoniazid for 3 days
Isoniazid induced varying degrees of hepatic steatosis in an inbred strain Mouse Diversity Panel (MDP) study. RNA was isolated from all animals for analysis of gene expression changes in the liver. The objective of this study was to identify gene expression changes that drive isoniazid-induced steat...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-55489 | biostudies-arrayexpress
ProteomicsHDL proteome across 93 mouse strains
High-density lipoproteins (HDL) are nanoparticles with >80 associated proteins, phospholipids, cholesterol and cholesteryl esters. We have identified and quantified the ultracentrifugation isolated HDL proteome across 93 strains of mice, a diverse inbred strains of mice, Hybrid Mouse Diversity Panel...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-24 | PXD009473 | Pride
Hdl Strains Mouse 
TranscriptomicsBone microarray profiles from the Hybrid Mouse Diversity Panel
Significant advances have been made in the discovery of genes affecting bone mineral density (BMD); however, our understanding of its genetic basis remains incomplete. In the current study, genome-wide association (GWA) and co-expression network analysis was used in the recently described Hybrid Mou...
ORGANISM(S): Mus musculus 
2011-02-25 | GSE27483 | GEO
ProteomicsLiver proteomics of the HMDP - Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease
Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease. Unfortunately, our understanding of the contributing pathways that initiate and advance hepatosteatosis to subsequent complications is still poorly understood. Here, we take advantage of r...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-01 | PXD007281 | Pride
Hmdp Hybrid mouse diversity panel Liver Proteome wide association study Genetic reference panel 
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