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UnknownBenzodioxane-Benzamides as FtsZ Inhibitors: Effects of Linker's Functionalization on Gram-Positive Antimicrobial Activity.
Not available
S-EPMC10740499 | biostudies-literature
ProteomicsComparative Studies to Uncover Further Mechanisms of Action of N-(1,3,4-oxadiazol-2-yl)benzamide Containing Antibacterial Agents
Drug-resistant bacterial pathogens still cause high levels mortality annually despite the availability of many antibiotics. Staphylococcus aureus (MRSA) is especially problematic and the rise in resistance to front line treatments like vancomycin and linezolid calls for new chemical modalities to tr...
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus (ncbitaxon:46170) 
2021-11-10 | MSV000088343 | MassIVE
UnknownDesign, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents.
Not available
S-EPMC6225228 | biostudies-literature
ProteomicsA novel antimalarial agent that inhibits protein synthesis in Plasmodium falciparum
Drug resistance to nearly all antimalarials following their rollout underscores the need for novel chemotypes with novel mode of action to replenish the antimalarial drug-development pipeline. We identified a novel class of compounds in the antimalarial armory. Compound 31, characterized by a hydrox...
ORGANISM(S): Plasmodium falciparum NF54 
2025-12-08 | PXD065399 | Pride
Drug discovery Drug resistance Hydroxy benzamides Antimalarial 
UnknownDiscovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
Not available
S-EPMC7734795 | biostudies-literature
TranscriptomicsHDAC inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability
Histone deacetylases (HDACs) are critical in the control of gene expression and dysregulation of their activity has been implicated in a broad range of diseases including cancer, cardiovascular and neurological diseases. HDAC inhibitors (HDACi) employing different zinc chelating functionalities such...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-GEOD-49158 | biostudies-arrayexpress
MetabolomicsMetabolomics profiling of traditional botanical concoctions: Agniastra, Brahmastra and Neemastra

This study employed a untargeted GC–MS and LC–MS metabolomics, to characterize metabolite profiles of botanical concoctions such as Agniastra (AG), Brahmastra (BR), and Neemastra (NM) used in Indian natural farming as biocontrol agents. GC–MS analysis showed organic acids (24%), organoheterocycli...

2025-12-29 | MTBLS13035 | MetaboLights
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