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ProteomicsRegression of Post-Prandial Cardiac Hypertrophy in Burmese Pythons is Mediated by FoxO1
As ambush-hunting predators that consume large prey after long intervals of fasting, Burmese pythons evolved with unique adaptations for regulating organ structure and function. Among these is cardiac hypertrophy that develops within three days following a meal (1, 2), which we previously showed was...
ORGANISM(S): Python bivittatus 
2024-09-12 | PXD054079 | Pride
Cardiac hypertrophy Autophagy Foxo1 Burmese python Hypertrophy regression 
TranscriptomicsTranscription profiling of hearts from DTG-positive mice before and after the induction of the transgene Akt1 at different time points to investigate molecular mechanisms involved in the development of cardiac hypertrophy and heart failure
To investigate molecular mechanisms involved in the development of cardiac hypertrophy and heart failure, a tetracycline-regulated transgenic system to conditionally switch a constitutively-active form of the Akt1 protein kinase on or off in the adult heart was developed. Short-term activation (2 we...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-3383 | biostudies-arrayexpress
GenomicsAntihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy
Antihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy
PRJNA675138 | ENA
TranscriptomicsRegression of Cardiac Hypertrophy and Attenuation of Progression to Heart Failure by Paricalcitol Therapy in Rats
Background: Vitamin D deficiency is associated with cardiac hypertrophy and heart failure, and vitamin D therapy prevents the progression of cardiac hypertrophy in animal models. Here, we examine whether vitamin D therapy regresses pre-existing cardiac hypertrophy, and prevents the progression to he...
ORGANISM(S): Rattus norvegicus 
2010-09-14 | E-GEOD-24110 | biostudies-arrayexpress
GenomicsRegression of Post-Prandial Cardiac Hypertrophy in Burmese Pythons is Mediated by FoxO1
Regression of Post-Prandial Cardiac Hypertrophy in Burmese Pythons is Mediated by FoxO1
PRJNA1133630 | ENA
TranscriptomicsRegression of Post-Prandial Cardiac Hypertrophy in Burmese Pythons is Mediated by FoxO1
As ambush-hunting predators that consume large prey after long intervals of fasting, Burmese pythons evolved with unique adaptations for regulating organ structure and function. Among these is cardiac hypertrophy that develops within three days following a meal (1, 2), which we previously showed was...
ORGANISM(S): Python bivittatus 
2024-07-16 | GSE271793 | GEO
TranscriptomicsSRF Overexpression Leads to Altered Expression of MicroRNAs and Contributes to Cardiac Hypertrophy
The role of SRF in the regulation of microRNA expression and microRNA biogenesis in cardiac hypertrophy has not been well established. In this report, we employed a distinct transgenic mouse model to study the impact of SRF on cardiac microRNA expression and microRNA biogenesis. Cardiac-specific ove...
ORGANISM(S): Mus musculus 
2011-02-16 | E-GEOD-23044 | biostudies-arrayexpress
GenomicsAntihypertrophic Memory after Regression of Exercise-induced Physiological Myocardial Hypertrophy
Background: Exercise can induce physiological myocardial hypertrophy (PMH), and former athletes can live 5-6 years longer than nonathletic controls, suggesting a benefit after regression of PMH. We previously reported that regression of pathological myocardial hypertrophy has antihypertrophic effect...
ORGANISM(S): Mus musculus 
2020-11-07 | GSE161030 | GEO
TranscriptomicsRegression of Cardiac Hypertrophy and Attenuation of Progression to Heart Failure by Paricalcitol Therapy in Rats
Background: Vitamin D deficiency is associated with cardiac hypertrophy and heart failure, and vitamin D therapy prevents the progression of cardiac hypertrophy in animal models. Here, we examine whether vitamin D therapy regresses pre-existing cardiac hypertrophy, and prevents the progression to he...
ORGANISM(S): Rattus norvegicus 
2010-09-14 | GSE24110 | GEO
UnknownA Conserved Mechanism of Cardiac Hypertrophy Regression through FoxO1.
Not available
S-EPMC10849654 | biostudies-literature
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