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GenomicsSETD2 loss sensitizes kidney cancer cells to DNA hypomethylating agents
SETD2 loss sensitizes kidney cancer cells to DNA hypomethylating agents
PRJNA927290 | ENA
Proteomicsthermal proteome profiling of hypomethylating agents in infant ALL
thermal proteome profiling of hypomethylating agents in infant ALL for elucidation of their mode of action.
ORGANISM(S): Homo sapiens (Human) 
2022-11-15 | PXD030539 | Pride
Decitabine Azacitidine Tpp Human Lc-ms/ms 
GenomicsDNA hypomethylating agents increase activation and cytolytic activity of CD8+ T-cells
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T-cells
PRJNA637641 | ENA
GenomicsDNA hypomethylating agents potentiate the efficacy of CD3 bispecific T cell engagers [scATAC-seq]
DNA hypomethylating agents potentiate the efficacy of CD3 bispecific T cell engagers [scATAC-seq]
PRJNA1366492 | ENA
GenomicsCMML Collection of WES, WGS, RNA-Seq and ERRBS data
We first performed a comprehensive analysis of the genome of 66 chronic myelomonocytic leukemia cases using whole exome (N=49) or whole genome (N=17) sequencing for paired leukemic-control DNA. Then, we realized serial analysis of whole exome sequence in 17 cases, completed with serial RNA sequencin...
EGAS00001001264 | EGA
GenomicsDNA hypomethylating agents potentiate the efficacy of CD3 bispecific T cell engagers [BiSulfite-seq]
DNA hypomethylating agents potentiate the efficacy of CD3 bispecific T cell engagers [BiSulfite-seq]
PRJNA1365923 | ENA
GenomicsHypomethylating agents sensitize diffuse large B-cell lymphoma to venetoclax
Hypomethylating agents sensitize diffuse large B-cell lymphoma to venetoclax
PRJNA926939 | ENA
TranscriptomicsSETD2 loss sensitizes kidney cancer cells to DNA hypomethylating agents
Large-scale sequencing efforts in Clear cell renal cell carcinoma (ccRCC) have found a high prevalence of mutations in chromatin-related genes.  Prominent within this group is SETD2, which is mutated in 15% of ccRCC and is associated with aggressive disease. SETD2 is a methyltransferase responsible ...
ORGANISM(S): Homo sapiens 
2024-07-01 | GSE223688 | GEO
GenomicsActivation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia
Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia
PRJNA640441 | ENA
UnknownHypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies.
Not available
S-EPMC12515712 | biostudies-literature
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