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TranscriptomicsDiet induced obesity is independent of metabolic endotoxemia, Tlr4 signalling and hypothalamic inflammation
A number of studies have proposed that excess food intake, particularly of high fat diets arise due dysregulation of homeostatic mechanisms regulating neuroendocrine control of appetite and energy balance. Current dogma suggests high fat diets invoke hypothalamic inflammation which reduces hypothala...
ORGANISM(S): Mus musculus 
2018-10-23 | E-MTAB-6929 | biostudies-arrayexpress
ProteomicsFoxp3+ regulatory T cells control hypothalamic inflammation
The central nervous system (CNS) hypothalamus controls systemic metabolism. Inflammatory CNS processes evolving upon exposure to calorie-rich diet are thought to promote impaired metabolic CNS control, thereby triggering obesity and Type-2 diabetes (T2D). However, immune cells relevant for maintaini...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-20 | PXD004498 | Pride
Hypothalamic inflammation T cells Lc-ms/ms 
GenomicsDiet induced obesity is independent of metabolic endotoxemia, Tlr4 signalling and hypothalamic inflammation
Diet induced obesity is independent of metabolic endotoxemia, Tlr4 signalling and hypothalamic inflammation
PRJEB27397 | ENA
UnknownDietary sugars, not lipids, drive hypothalamic inflammation.
Not available
S-EPMC5518723 | biostudies-literature
TranscriptomicsTNFalpha and IL-6 induced anorexia: effects on serotonin turnover
Anorexia can occur as a serious complication of chronic disease. Increasing evidence suggests that inflammation plays a major role, along with a hypothalamic dysregulation characterized by locally elevated serotonin levels. The present study was undertaken to further explore the connections between ...
ORGANISM(S): Mus musculus 
2016-05-31 | E-GEOD-69151 | biostudies-arrayexpress
UnknownHypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation.
Not available
S-EPMC6284237 | biostudies-literature
UnknownComparative Analysis of Hypothalamic Responses to Stress and Glutamine Supplementation in Diet-Induced Obese Mice: A Study of Sex Differences.
Not available
S-EPMC12858480 | biostudies-literature
UnknownIncreased hypothalamic serotonin turnover in inflammation-induced anorexia.
Not available
S-EPMC4875640 | biostudies-literature
UnknownDeficiency of Tristetraprolin Triggers Hyperthermia through Enhancing Hypothalamic Inflammation.
Not available
S-EPMC8037390 | biostudies-literature
TranscriptomicsInflammatory bladder response
Bladders examined at 1, 4 and 24 hours after lipopolysaccharide, substance P or ovalbumin challenge.
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-597 | biostudies-arrayexpress
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