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MetabolomicsMetabolic Profiles Under Hypoxic Stress: Adolescent Athletes' Experience

Hypoxic training is a method by athletes to enhance their performance at sea level or improve their cardiovascular endurance in moderate-altitude competitions. Comparative studies involving populations from low and moderate altitudes offer an opportunity to understand the mechanisms behind adapta...

2025-02-27 | MTBLS10841 | MetaboLights
TranscriptomicsDivergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/Insulin/IGF-receptor pathway
To identify genes that selectively regulate hypoxic sensitivity, we compared the whole-organismal transcriptomes of three daf-2 reduction-of-function alleles, all of which are hypoxia resistant, thermotolerant, and long lived but differ in their rank of severities for these phenotypes. The transcrip...
ORGANISM(S): Caenorhabditis elegans 
2010-06-20 | E-GEOD-18601 | biostudies-arrayexpress
GenomicsGenome-wide maps of DNase I sensitivity in normoxic and hypoxic cells
Genome-wide maps of DNase I sensitivity in normoxic and hypoxic cells
PRJNA420850 | ENA
ProteomicsRibosomal and tRNA Biogenesis Interact to Control Hypoxic Injury and Translation
Protein translation is an essential cellular process, but paradoxically, it can also promote aging and other stresses. In a screen for mutations that protect C. elegans from hypoxic stress, we isolated multiple genes that impact translation, including a ribosomal RNA helicase gene, ddx-52, tRNA bios...
ORGANISM(S): Caenorhabditis elegans 
2022-02-15 | PXD017267 | Pride
Ribosomal biogenesis Silac analysis of protein synthesis rate Lfq and tmt quantification Hypoxic sensitivity 
TranscriptomicsLong-term adaptation to hypoxic conditions - Febit transcriptome analysis
Aspergillus fumigatus is an opportunistic, airborne pathogen causing invasive aspergillosis in immunocompromised patients. During the infection process A. fumigatus is challenged by hypoxic microenvironments occurring in inflammatory, necrotic tissue. To gain further insights into the adaptation mec...
ORGANISM(S): Aspergillus fumigatus 
2014-07-01 | E-MTAB-2699 | biostudies-arrayexpress
GenomicsGenome-wide maps of DNase I sensitivity in normoxic and hypoxic cells
We report genome-wide maps of DNase I sensitivity in normoxic and hypoxic cells to provide information on changes in chromatin status in response to oxygen availability.
ORGANISM(S): Homo sapiens 
2017-12-03 | GSE107619 | GEO
GenomicsTranscriptomic analysis indicates a role for oxidative phosphorylation in postnatal development of rat carotid body hypoxic sensitivity
Transcriptomic analysis indicates a role for oxidative phosphorylation in postnatal development of rat carotid body hypoxic sensitivity
PRJNA1063303 | ENA
TranscriptomicsDivergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/Insulin/IGF-receptor pathway
To identify genes that selectively regulate hypoxic sensitivity, we compared the whole-organismal transcriptomes of three daf-2 reduction-of-function alleles, all of which are hypoxia resistant, thermotolerant, and long lived but differ in their rank of severities for these phenotypes. The transcrip...
ORGANISM(S): Caenorhabditis elegans 
2009-10-31 | GSE18601 | GEO
UnknownDivergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway.
Not available
S-EPMC2775958 | biostudies-literature
UnknownHsa-miR-423-5p selectively loaded in hypoxic exosomes reduces the sensitivity of normoxic hepatocellular carcinoma to sorafenib via autophagy.
Not available
S-EPMC12659515 | biostudies-literature
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