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TranscriptomicsVNO_MOE_microarrays
Transcriptional profile of the main olfactory epithelium (MOE) and the vomeronasal organ (VNO) of male wild type mice
ORGANISM(S): Mus musculus 
2013-12-23 | E-MTAB-2163 | biostudies-arrayexpress
TranscriptomicsRNAseq of mouse presomitic mesoderm segments along the anteroposterior embryo axis.
Somitogenesis is the segmentation of the developing embryonic body axis into somites and is guided by oscillating genes, which create waves of expression that travel across the presomitic mesoderm (PSM) from posterior to anterior. Upon arrival of a wave at the PSM's anterior end, a new somite is for...
ORGANISM(S): Mus musculus 
2017-12-01 | E-MTAB-6155 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq of whole B6 mouse E8.25 embryos
Gastrulation represents a pivotal point in mammalian development, when the basic body plan is established and cells are specified into one of the three germ layers. This is followed by rapid diversification into specific lineages and the appearance of the various cell types required to build each of...
ORGANISM(S): Mus musculus 
2017-12-01 | E-MTAB-6153 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq of whole mouse E8.25 embryos
Gastrulation represents a pivotal point in mammalian development, when the basic body plan is established and cells are specified into one of the three germ layers. This is followed by rapid diversification into specific lineages and the appearance of the various cell types required to build each of...
ORGANISM(S): Mus musculus 
2017-12-01 | E-MTAB-5728 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of Ctcf hemizygous mouse embryonic fibroblasts: RNA-seq
CTCF is a highly conserved and ubiquitously expressed protein involved in several fundamental processes such as fine-tuning gene expression, imprinting, X-chromosome inactivation and 3D chromatin organisation. To understand the impact of differences in the concentration of CTCF abundance on these pr...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6259 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of Ctcf hemizygous mouse embryonic fibroblasts: HiC
CTCF is a highly conserved and ubiquitously expressed protein involved in several fundamental processes such as fine-tuning gene expression, imprinting, X-chromosome inactivation and 3D chromatin organisation. To understand the impact of differences in the concentration of CTCF abundance on these pr...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6262 | biostudies-arrayexpress
GenomicsMolecular profiling of Ctcf hemizygous mouse embryonic fibroblasts: ChIP-seq
CTCF is a highly conserved and ubiquitously expressed protein involved in several fundamental processes such as fine-tuning gene expression, imprinting, X-chromosome inactivation and 3D chromatin organisation. To understand the impact of differences in the concentration of CTCF abundance on these pr...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6261 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-sequencing of OMP-GFP mouse olfactory sensory neurons
We sequenced the transcriptome of 34 single olfactory sensory neurons (OSNs) manually picked from OMP-GFP mice, ensuring the cells expressed high levels of GFP, a marker of mature OSNs. We pooled the olfactory mucosa from 2 male and 2 female animals, to obtain single-cell suspensions for cell pickin...
ORGANISM(S): Mus musculus 
2020-02-04 | E-MTAB-8285 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiles of C3H/HeJ mouse liver tumours
Male C3H/HeOuJ mice are susceptible to spontaneous liver neoplasms. We aged a cohort of mice for up to 76 weeks and isolated liver tumours. Tumours were bisected: one half was snap frozen in liquid nitrogen for RNA extraction and the other half of the tumour was processed for histological examinatio...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6971 | biostudies-arrayexpress
TranscriptomicsMapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens
The vast majority of complex disease associations cannot be cleanly mapped to a gene, as they often lie within the non-cding fraction of the genome. Immune disease-associated variants are enriched within regulatory elements, such as distal enhancers, found in T cell-specific open chromatin regions. ...
ORGANISM(S): Homo sapiens 
2024-01-08 | E-MTAB-13324 | biostudies-arrayexpress
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