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TranscriptomicsTranscription profiling by array of primary human hepatocytes derived from hepatitis C patients treated with type III interferons (IFNs) for 6 or 24 hours
Recent identification of IL28B gene polymorphisms associated with hepatitis C virus (HCV) clearance suggests a role for type III interferons (IFNs) in hepatitis C infection. The function of type III IFNs in intrinsic antiviral immunity is poorly understood. Here we show that HCV infection of primar...
ORGANISM(S): Homo sapiens 
2012-03-09 | E-GEOD-31193 | biostudies-arrayexpress
GenomicsAnalysis of differentiatng monocytes transcriptome changes in response to type I IFNs
Analysis of differentiatng monocytes transcriptome changes in response to type I IFNs
PRJNA791383 | ENA
GenomicsType I IFNs facilitate innate immune control of opportunistic bacteria in the macrophage cytosol
Type I IFNs facilitate innate immune control of opportunistic bacteria in the macrophage cytosol
PRJNA692977 | ENA
TranscriptomicsTranscription profiling of human endothelial and fibroblast cells isolated from umbilical cord veins treated with interferons to identify genes regulated by interferons
IFNs are highly pleiotropic cytokines also endowed with marked anti-angiogenic activity. In this study, the mRNA expression profiles of endothelial cells (EC) exposed in vitro to IFN-alpha, IFN-beta, or; IFN-gamma were determined. We found that in HUVEC as well as in other EC types 175 genes were up...
ORGANISM(S): Homo sapiens 
2009-04-08 | E-GEOD-3920 | biostudies-arrayexpress
TranscriptomicsAnalysis of differentiatng monocytes transcriptome changes in response to type I IFNs
To analyze the transcriptome changes of differentiating monocytes in response to type I IFNs, RNA seq was performed. The MACS-purified mouse BM monocytes were cultured in the presence or absence of I IFNs for 12 h or 24h under the condition of M-CSF, samples were harvested for total RNAs and subject...
ORGANISM(S): Mus musculus 
2022-12-31 | GSE192418 | GEO
UnknownIFNs Drive Development of Novel IL-15-Responsive Macrophages.
Not available
S-EPMC7415599 | biostudies-literature
GenomicsType-I IFNs in EAE drive synaptic transcriptional responses in neurons and astrocytes in the brain
Type-I IFNs in EAE drive synaptic transcriptional responses in neurons and astrocytes in the brain
PRJNA1525932 | ENA
UnknownA sensitive assay for measuring whole-blood responses to type I IFNs.
Not available
S-EPMC11459193 | biostudies-literature
UnknownIncontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases.
Not available
S-EPMC11448874 | biostudies-literature
TranscriptomicsType I IFNs facilitate innate immune control of opportunistic bacteria in the macrophage cytosol
The mammalian immune system is constantly challenged by signals from both pathogenic and non-pathogenic microbes. Many of these non-pathogenic microbes have pathogenic potential if the immune system is compromised. The importance of type I interferons (IFNs) in orchestrating innate immune responses ...
ORGANISM(S): Mus musculus 
2021-01-19 | GSE165020 | GEO
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