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MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
TranscriptomicsGene expression change induced by bisphenol A in mouse urogenital sinus
Bisphenol A (BPA), an endocrine-disrupting chemical (EDC), is a well-known, ubiquitous estrogenic chemical. To investigate the effects of fetal exposure to low-dose BPA on the development of the prostate, we first examined the alterations of in situ sex steroid hormonal environment in the mouse urog...
ORGANISM(S): Mus musculus 
2010-12-06 | E-GEOD-24928 | biostudies-arrayexpress
UnknownCurrent Status of Prurigo Nodularis in Japan: A Retrospective Study Using a Health Insurance Claims Database.
Not available
S-EPMC11943442 | biostudies-literature
UnknownA phase 2, randomized, double-blind, vehicle-controlled trial of tapinarof cream in Japanese pediatric patients with atopic dermatitis.
Not available
S-EPMC11807361 | biostudies-literature
UnknownInfluenza A Virus M2 Protein: Roles from Ingress to Egress.
Not available
S-EPMC5751251 | biostudies-literature
UnknownTapinarof cream for the treatment of plaque psoriasis: Efficacy and safety results from 2 Japanese phase 3 trials.
Not available
S-EPMC11484133 | biostudies-literature
TranscriptomicsIdentification of Myt1 as a subunit of the neural cell type-specific LSD1 complex
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. Recently, dynamic epigenomic regulation, including chromatin remodeling and histone modifications by tra...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-49685 | biostudies-arrayexpress
UnknownSecuring human resources for Japan's aging population: a mixed methods study of job satisfaction and well-being among Southeast Asian long-term care workers in Japan.
Not available
S-EPMC11428807 | biostudies-literature
TranscriptomicsTranscription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function.
Pulmonary alveolar proteinosis (PAP) results from a dysfunction of alveolar macrophages (AMs), chiefly due to disruptions in the signaling of granulocyte macrophage colony-stimulating factor (GM-CSF). We found that mice deficient for the B lymphoid transcription repressor BTB and CNC homology 2 (Bac...
ORGANISM(S): Mus musculus 
2014-01-15 | E-GEOD-54050 | biostudies-arrayexpress
UnknownTo be red or white: lineage commitment and maintenance of the hematopoietic system by the "inner myeloid".
Not available
S-EPMC6886412 | biostudies-literature
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