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ProteomicsIgf2bp2 deletion reduces energy metabolism, gIgf2bp2 deletion reduces energy metabolism, growth signaling, and aging of hematopoietic stem cells in micerowth signaling, and aging of hematopoietic stem cells in mice
Increasing evidence links metabolic activity and cell growth to decline in hematopoietic stem cell (HSC) function during aging. The Lin28b/Hmga2 pathway controls tissue development and in the hematopoietic system the postnatal downregulation of this pathway causes a decrease in self renewal of adult...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD018535 | Pride
Mitochondrial metabolism Protein synthesis and mtor/pi3k-dependent differentiation of hematopoietic stem cells. Igf2bp2 drives glycolysis 
UnknownIGF2BP2 regulates gastric cancer radiotherapy resistance through HIF1α-mediated glycolysis.
Not available
S-EPMC12134386 | biostudies-literature
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