Igg3 - OmicsDI

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Unknown (657)
Transcriptomics (210)
Proteomics (125)
Genomics (84)
Metabolomics (12)
Models (3)
Other (2)
Multiomics (1)

Organisms

Homo sapiens (145)
Mus musculus (122)
Aerococcus urinae NBRC 15544 = CCUG 36881 (10)
Andropogon gerardi (10)
Saccharomyces cerevisiae (9)
Bos taurus (6)
Rattus norvegicus (4)
Saccharomyces cerevisiae W303 (3)
Macaca mulatta (2)
Sus scrofa (2)
Drosophila melanogaster (2)
Schistosoma mansoni (2)
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dust metagenome (1)
human nasopharyngeal metagenome (1)
Oxytricha trifallax (1)
Mustela putorius furo (1)
unidentified (1)
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Severe acute respiratory syndrome coronavirus 2 (1)

Organisms

Mus musculus (8)
Homo sapiens (4)
Cricetulus griseus (1)
Schistosoma mansoni (1)
Vicugna pacos (1)

Repository

biostudies-arrayexpress (265)
MassIVE (82)
ENA (17)
EGA (13)
MetaboLights (12)
geo (11)
jPOST (10)
pride (10)
iProX (8)
PanoramaPublic (4)
Cell Collective (3)
GPMDB (1)

Tissue

Blood serum (4)
Blood plasma (3)
Blood cell (2)
B cell (1)
Blood (1)
Milk (1)

Disease

Normal (2)
Control (1)
Not Available (1)
Avian influenza (1)
Prostate adenocarcinoma (1)
Stomach carcinoma (1)

Technology Type

Mass Spectrometry (10)
Mass spectrometry (6)
Mass spectrometry assay (6)
Shotgun proteomics (6)
Illumina HiSeq 2000 (1)
Affinity purification coupled with mass spectrometry proteomics (1)
All-ion fragmentation (1)
Bottom-up proteomics (1)
Data-dependent acquisition (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (25)
Illumina HiSeq 2500 (11)
NextSeq 2000 (10)
Illumina HiSeq 4000 (6)
NextSeq 500 (6)
Illumina NovaSeq X (5)
NextSeq 550 (4)
Illumina HiSeq 1500 (3)
Illumina HiSeq 2000 (3)
SnakePipes 3.4 (1)
NEBNext Ultra II DNA Library Prep Kit (1)
KAPA RNA HyperPrep Kit (1)
Deeptools, macs3 (1)
KAPA EvoPrep Kit (1)
NCounter Pro and nCounter Pro Analysis System (1)
Nanodrop 2000c spectrophotometer (1)
GenePix4000B (1)
None (1)
Not provided (1)
RNeasy Mini Kit (1)
NA (1)
N/a (1)
TruSeq (Illumina, Novogene, Genomic Centre Cambridge, CB4 0FW, UK.) (1)
NanoDrop spectrophotometer and the Agilent 2100 Bioanalyzer (1)
Histopaque-1077,FACSAria Fusion Sorter,Flow Cytometer (1)
DNBSEQ-T7 (1)
BGISEQ-500 (1)
Illumina MiSeq (1)
Illumina HiSeq 3000 (1)
Instrument (1)

Publication Date

2014 (45)
2024 (39)
2023 (38)
2026 (29)
2013 (28)
2025 (27)
2010 (21)
2015 (20)
2016 (19)
2021 (18)
2011 (18)
2022 (17)
2012 (17)
2020 (13)
2018 (12)
2008 (12)
2019 (11)
2017 (4)
2007 (3)
2009 (2)
2005 (1)
2004 (1)

CHEBI ID

CHEBI:17295 (3)
CHEBI:17992 (2)
CHEBI:16325 (2)
CHEBI:16359 (2)
CHEBI:80774 (2)
CHEBI:30768 (2)
CHEBI:28484 (2)
CHEBI:16135 (2)
CHEBI:30772 (2)
CHEBI:18050 (2)
CHEBI:16865 (2)
CHEBI:15741 (2)
CHEBI:18012 (2)
CHEBI:17895 (2)
CHEBI:18089 (2)
CHEBI:229589 (1)
CHEBI:229588 (1)
CHEBI:229587 (1)
CHEBI:229586 (1)
CHEBI:229585 (1)
CHEBI:229583 (1)
CHEBI:229582 (1)
CHEBI:229581 (1)
CHEBI:90434 (1)
CHEBI:229584 (1)
CHEBI:229048 (1)
CHEBI:176760 (1)
CHEBI:60050 (1)
CHEBI:137102 (1)
CHEBI:58115 (1)

Metabolite Name

7-Methylguanine (3)
Indole (3)
Choline (3)
Guanine (3)
L-Tryptophan (3)
Adenine (3)
L-Tyrosine (3)
L-Phenylalanine (3)
Taurochenodeoxycholic Acid (2)
Aminoacetone (2)
Cyclopamine (2)
N-Isovaleroylglycine (2)
3-Pentadecylphenol (2)
Histidylproline (2)
4-Vinylcyclohexene (2)
Geranylcitronellol (2)
Geranylgeraniol (2)
Phenol (2)
4-Propylphenol (2)
2-Piperidinone (2)
Curcumol (2)
Uracil (2)
Thymine (2)
Thiamine (2)
Octadecanamide (2)
Lumichrome (2)
Dihydroactinidiolide (2)
Diethanolamine (2)
Betaxolol (2)
3-Ketosphingosine (2)

First Public Date

2024 (4)
2023 (4)
2021 (3)
2026 (2)
2025 (1)
2019 (1)
2017 (1)
2014 (1)

Classification

helminths (1)

Study type

Transcription profiling by array (95)
ChIP-seq (48)
RNA-seq of coding RNA (29)
RNA-seq of coding RNA from single cells (16)
Other (11)
Proteomic profiling by array (9)
CUT&RUN (9)
ChIP-chip by tiling array (8)
RIP-seq (7)
DNA-seq (5)
ChIP-chip by array (4)
RNA-seq of total RNA (3)
Human - Single-cell sequencing (2)
Antigen profiling (2)
Transcription profiling by RT-PCR (2)
Single nucleus RNA sequencing (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA (2)
Unknown experiment type (1)
RNA-seq of non coding RNA from single cells (1)
MeDIP-seq (1)
RIP-chip by array (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
MBD-seq (1)
ATAC-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2023 (82)
2021 (79)
2022 (75)
2025 (67)
2014 (64)
2024 (63)
2020 (59)
2019 (54)
2018 (46)
2016 (43)
2015 (41)
2013 (41)
2017 (33)
2012 (29)
2011 (29)
2010 (29)
2026 (24)
2008 (16)
2009 (12)
2007 (11)
2006 (7)
2005 (3)
2004 (3)
2003 (3)
2000 (3)
2002 (2)
1999 (1)
1997 (1)
1993 (1)
1979 (1)

Lab affiliation

1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands 2Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands (1)
Center for Proteomics and Metabolomics, Leiden Universtity Medical Center, The Netherlands (1)
Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, N0. 1037 Luoyudong Road, Hongshan District, Wuhan 430074 (1)
Fudan University (1)
Institute of Immunology Rikshospitalet, University hospitla Oslo, Norway (1)
LUMC (1)
Medical School of Nanjing University, China (1)
Sanquin Research, NL (1)
West China Hospital, Sichuan University (1)

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Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains

IgG3 is unique among the IgG subclasses due to its extended hinge, allotypic diversity and enhanced effector functions, including highly efficient pathogen neutralization and complement activation. It is also underrepresented as an immunotherapeutic candidate, partly due to a lack of structural info...

ORGANISM(S): Homo sapiens (Human)

2023-10-24 | PXD039049 | Pride