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TranscriptomicsExpression data from (bezafibrate treated-wild type, Clock mutant, and PPARalpha-null) mouse liver
A functional interaction between peroxisome proliferator-activated receptor alpha (PPARalpha) and components of the circadian clock has been suggested; however, it remains to be clarified whether those transcriptional factors interact with each other to regulate the expression of their target genes....
ORGANISM(S): Mus musculus 
2010-06-14 | E-GEOD-20513 | biostudies-arrayexpress
Transcriptomics5/6 nephrectomy (5/6Nx) effect on the brain
Chronic kidney disease (CKD) is a very important problem in global health treatment. CKD increases the disease risk of apoplexy, cardiac failure and cardiac infarction. In addition, neurological complications, including depression and restless legs syndrome, occur in almost all CKD patients; however...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-35134 | biostudies-arrayexpress
Transcriptomics5/6 nephrectomy (5/6Nx) effect on the liver
Chronic renal failure (CRF) is associated with a decrease in drug metabolism. The present study investigated the repercussions of CRF on liver cytochrome P450 (CYPs), but the mechanisms have been little explored. On the other hand, the expression of several CYP genes exhibits circadian rhythm. Here ...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-35135 | biostudies-arrayexpress
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