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TranscriptomicsmiRNA profiling of HPCX1 linked prostate cancer patients and their healthy brothers
MicroRNA expression levels in the lymphoblastic cells of prostate cancer patients and their healthy brothers from HPCX1 linked prostate cancer families were analyzed to trace variants that might alter miRNA expression and explain partly an inherited genetic predisposion to prostate cancer. MicroRN...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-24201 | biostudies-arrayexpress
TranscriptomicsIdentification of truncating mutations in HPCX1 families with NMD technology
In this study, nonsense-mediated mRNA decay (NMD) inhibition was used for the discovery of truncating mutations. Six prostate cancer (PRCA) patients and their healthy brothers were selected from a group of HPCX1-linked families. mRNA was isolated from their lymphoblastic cells after pharmacological ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-24204 | biostudies-arrayexpress
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