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MetabolomicsHuman Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case of Yersinia pestis
Metabolomic approaches, such as in clinical applications of living individuals, have shown potential use for solving questions regarding the past when applied to archaeological material. Here, we study for the first time the potential of this Omic approach as applied to metabolites extracted from ar...
2024-03-15 | MTBLS7394 | MetaboLights
TranscriptomicsHuman cell toxicogenomic analysis links reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts
The monohaloacetic acids (monoHAAs) are generated as byproducts during the disinfection of drinking water and are cytotoxic, genotoxic, mutagenic, and teratogenic. Iodoacetic acid (IAA) toxicity was mitigated by antioxidants, suggesting the involvement of oxidative stress. Other monoHAAs may share a...
ORGANISM(S): Homo sapiens 
2013-08-11 | E-GEOD-49698 | biostudies-arrayexpress
Transcriptomicscomparison of the transcriptome of the conditional afpig-a mutant and the wild-type
In order to gain a better understanding of the mechanism of increased cell death triggered by deficient GPI anchoring, we constructed a whole genome microarray using the Agilent eArray 5.0 program.The chip specification is 8M-CM-^W15K. The genome sequences were downloaded from the following site:htt...
ORGANISM(S): Aspergillus fumigatus 
2013-07-22 | E-GEOD-42499 | biostudies-arrayexpress
UnknownResource Use in the Randomized Master Protocol for Immune Modulators for Treating COVID-19 (ACTIV-1 IM): A Secondary Data Analysis.
Not available
S-EPMC11600409 | biostudies-literature
TranscriptomicsThe Poly(C) binding protein Pcbp2, and its retrotransposed derivative Pcbp1, are independently essential to mouse development
RNA-binding proteins participate in a complex array of post-transcriptional controls essential to cell-type specification and somatic development. Despite their detailed biochemical characterizations, the degree to which each RNA-binding protein impacts on mammalian embryonic development remains in...
ORGANISM(S): Mus musculus 
2015-11-05 | E-GEOD-72491 | biostudies-arrayexpress
TranscriptomicsGene expression in the islets of 12 wk old Non-Obese Diabetic (NOD) mice and healthy control NOD.B10 mice
Gene expression in the islets of NOD and NOD.B10 mice at 12 weeks of age, prior to the onset of destructive insulitis. The pancreata of NOD and NOD.B10 mice (n=6) were frozen and islets were isolated by laser capture microdissection. Cryosections (8 M-NM-
ORGANISM(S): Mus musculus 
2013-04-10 | E-GEOD-45897 | biostudies-arrayexpress
MetabolomicsExamination of human osteoarchaeological remains as a feasible source of polar and apolar metabolites to study past conditions
Metabolomics is a modern tool that aids in our understanding of the molecular changes in organisms. Archaeological science is a branch of archaeology that explores different archaeological materials using modern analytical tools. Human osteoarchaeological material are a frequent finding in archaeolo...
2022-07-04 | MTBLS4437 | MetaboLights
UnknownA phase II trial of S-1 and oxaliplatin in patients with advanced hepatocellular carcinoma.
Not available
S-EPMC5838934 | biostudies-literature
UnknownReconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage.
Not available
S-EPMC6168464 | biostudies-literature
UnknownA randomized controlled trial evaluating the short-term efficacy of a single-administration intramuscular injection with the fixed combination of thiocolchicoside-diclofenac versus diclofenac monotherapy in patients with acute moderate-to-severe low back pain.
Not available
S-EPMC10257820 | biostudies-literature
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