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ProteomicsHCMV deletion models enable the identification of physiologically relevant T-cell epitopes
In healthy individuals, immune control of persistent human cytomegalovirus (HCMV) infection is effectively mediated by virus-specific CD4+ and CD8+ T cells. However, identification of the repertoire of T-cell specificities for HCMV is hampered by the immense protein coding capacity of this betaherpe...
ORGANISM(S): Homo sapiens (Human) Cytomegalovirus 
2019-11-20 | PXD013120 | Pride
Hla Hla ligandomics T-cell epitopes Human cytomegalovirus Immunoevasin deletion Immunotherapy Mhc affinity prediction 
UnknownThe Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the exocytic and endocytic pathways.
Not available
S-EPMC3028889 | biostudies-literature
UnknownThe immune evasion paradox: immunoevasins of murine cytomegalovirus enhance priming of CD8 T cells by preventing negative feedback regulation.
Not available
S-EPMC2583666 | biostudies-literature
UnknownCytomegalovirus m154 hinders CD48 cell-surface expression and promotes viral escape from host natural killer cell control.
Not available
S-EPMC3953435 | biostudies-literature
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