Immunosuppressant

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DNA damage responses and cancer lab Department of Human Genetics Leiden University Medical Center Eithovenweg 20 2333ZC Leiden The Netherlands (1)
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Genomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity

The use of calcineurin inhibitor (CI) immunosuppressants has significantly improved the early allograft survival rate in organ transplantation. However, CI therapy has been associated with chronic nephrotoxicity, which limits their long-term utility. In order to understand the mechanisms of the toxi...

ORGANISM(S): Rattus norvegicus

2011-11-23 | E-GEOD-19366 | biostudies-arrayexpress

Transplant immunosuppressant therapies induce unique functional changes in and re-shape gut immune homeostasis

PRJNA1215996 | ENA

Transplant immunosuppressant therapies induce unique functional changes in and re-shape gut immune homeostasis

Current immunosuppressants effectively suppress adaptive and innate immune responses, but their broad, antigen-non-specific effects often result in significant complications. Here we investigated understudied immunosuppressant effects of four major immunosuppressant classes including tacrolimus, pre...

ORGANISM(S): Mus musculus

2025-06-24 | GSE288074 | GEO

Immunosuppressant adherence in adult outpatient hematopoietic cell transplant recipients.

Not available

S-EPMC10622331 | biostudies-literature

Biosynthesis of the Immunosuppressant (-)-FR901483.

Not available

S-EPMC8094545 | biostudies-literature

Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapy.

Not available

S-EPMC7428791 | biostudies-literature

Genomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity