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UnknownConstruction of an immune-related lncRNA signature pair for predicting oncologic outcomes and the sensitivity of immunosuppressor in treatment of lung adenocarcinoma.
Not available
S-EPMC9101821 | biostudies-literature
TranscriptomicsTranscriptome profiling of THP-1 cells treated with chemicals
We profiled the transcriptome of Dexamethasone-, Tofacitinib-, Tacrolimus-, Prednisolone-, sodium lauryl sulfate (SLS)-, Aciclovir-, Benzoic acid-, Genistein-, Ribavirin-, Mercuric chloride-, Cyclosporine- and LPS-treated monocytes and without chemical-treated (basal, vehicle) monocytes. A Bioconduc...
ORGANISM(S): Homo sapiens 
2021-12-11 | GSE190511 | GEO
UnknownZUGC-RNA degradation generates immunosuppressor to evade immune responses in eukaryotes.
Not available
S-EPMC11838226 | biostudies-literature
TranscriptomicsGene expression profile of isolated splenic NK cells from mice treated with ptaquiloside and/or selenium
To better understand the immunosuppressor mechanism of ptaquiloside in splenic NK cells and the reversion of this effect by selenium, we have employed whole genome microarray expression profile to identify genes associated with immunosuppression. Among 89 genes induced by ptaquiloside treatment in s...
ORGANISM(S): Mus musculus 
2013-07-24 | GSE30629 | GEO
TranscriptomicsGene expression profiling dendritic cells (DC) producing IL-10
To identify factors associated with the immunosuppressor activity of IL-10+ DC, these cells were obtained from VertX mice immunized with OVA+imiquimod and compared with IL-10- DCs from the same mice and from VertX mice, either untreated or vaccinated with OVA+poly(I:C).
ORGANISM(S): Mus musculus 
2022-11-02 | GSE198973 | GEO
TranscriptomicsAge-associated modulation of TREM1/TREM2 expressing macrophages promotes melanoma progression and metastasis
Aging is a known risk factor for melanoma, yet the mechanisms underlying melanoma progression and metastasis in the older population remain largely unexplored. Among remaining gaps is the role of changes in melanoma microenvironment in key phenotypes exacerbated by age. Here we demonstrate that age ...
ORGANISM(S): Mus musculus 
2025-02-27 | GSE280640 | GEO
TranscriptomicsRNA-Sequencing Reveals the Changes of Gene Expression Profile in the Lipopolysaccharide-induced Immunoresponsed Uterine Body after the Immunosuppressant Cyclosporine A-treatment
Infection of Gram-negative bacteria in female genital tract causes systematic immune-response and reproductive dysfunction. Immunosuppressor Cyclosporine A (CsA) is widely used in the treatment of genital tract immune response, however, the knowledge on the changes of transcriptome after CsA inhibit...
ORGANISM(S): Oryctolagus cuniculus 
2020-06-13 | GSE152343 | GEO
UnknownThe introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma.
Not available
S-EPMC10991124 | biostudies-literature
TranscriptomicsGene expression profiles of effector T cells induced by mTOR inhibition
To further develop our gene expression approach to treatment of autoimmunity, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon immunosuppressor treatment responsible for inhibition of T cell effector functions. Huma...
ORGANISM(S): Homo sapiens 
2012-09-05 | GSE29606 | GEO
UnknownTargeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma.
Not available
S-EPMC3896661 | biostudies-literature
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