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GenomicsTranscriptome changes in patients with severely impaired spermatogenesis
Transcriptome changes in patients with severely impaired spermatogenesis
PRJNA607268 | ENA
UnknownSperm cryopreservation for impaired spermatogenesis.
Not available
S-EPMC9874962 | biostudies-literature
TranscriptomicsTranscriptome changes in patients with severely impaired spermatogenesis
Aiming to identify gene expression signatures underlying the pathogenesis of infertility, we performed global gene expression profiling on testis samples in patients with severely impaired and normal spermatogenesis.
ORGANISM(S): Homo sapiens 
2020-02-19 | GSE145467 | GEO
ProteomicsSpecific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis
Protein phosphatase 6 (PP6) is a member of the PP2A-like subfamily, which plays significant roles in numerous fundamental biological activities. We found that PPP6C plays important roles in male germ cells recently. Spermatogenesis is supported by the Sertoli cells in seminiferous epithelium. In thi...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD028051 | Pride
Ppp6c Phosphoproteome Sertoli cells Spermatogenesis Β-catenin 
GenomicsMethylome study on human spermatogenic cells
DNA methylation is an important regulator of the chromatin structure and is necessary for gene expression stability and maintenance of cell identitiy. However, to which extent DNA methylation changes during the key differentiation steps of human spermatogenesis remains largely unkown. Here, we gener...
EGAS00001007449 | EGA
UnknownHighly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis.
Not available
S-EPMC4972306 | biostudies-literature
Genomics
Sequencing of fecal microbes in mice with impaired spermatogenesis
PRJNA983564 | ENA
UnknownCellular Therapy via Spermatogonial Stem Cells for Treating Impaired Spermatogenesis, Non-Obstructive Azoospermia.
Not available
S-EPMC8304133 | biostudies-literature
UnknownKnockout of BRD7 results in impaired spermatogenesis and male infertility.
Not available
S-EPMC4754950 | biostudies-literature
TranscriptomicsTranscription profiling of testis biopsies to investigate testis developmental gene expression in cryptorchid boys at risk of azoospermia
Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25518 | biostudies-arrayexpress
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