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ProteomicsHepatocellular Metabolic Profile: Understanding Post-Thawing Metabolic Shift in Primary Hepatocytes in vitro
Positive and negative-mode metabolomics data from a time-course experiment for unexposed cells during a 24-hour time course, investigating the changes in metabolism of primary human hepatocytes in vitro post-thawing.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-04-01 | MSV000097484 | MassIVE
ProteomicsFenbendazole Met ID_in vitro_cross-species_FBMN
Fenbendazole Met ID by an integrative approach using feature-based molecular networking of cross-species in vitro liver microsomal and hepatocellular incubation.
ORGANISM(S): Canis Lupus Familiaris (ncbitaxon:9615) Macaca Fascicularis (ncbitaxon:9541) Cd1 Mouse Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095554 | MassIVE
MetabolomicsComparison of popular enrichment methods for untargeted in vitro metabolomics.

Introduction

Untargeted metabolomics is a popular method by which researchers measure a large portion of the metabolites present in a biological system at once. This approach usually results in complex data sets containing tens to hundreds of thousands of observations whi...

2025-08-11 | MTBLS12332 | MetaboLights
GenomicsTargeted sequencing of in vitro colonies bulks
In this study we will perform targeted sequencing on the bulk samples of in vitro colonies
EGAS00001003175 | EGA
GenomicsWhole genome sequencing of in vitro colonies
In this study we will perform whole genome sequencing on in vitro colonies. Colonies of various sizes (100-300 cells) will be collected for somatic mutation analysis.
EGAS00001003112 | EGA
TranscriptomicsIn vitro activation and reversion of human primary hepatic stellate cells
Liver fibrosis is characterized by the excessive formation and accumulation of matrix proteins as a result of wound healing in the liver. A main event during fibrogenesis is the activation of the liver resident quiescent hepatic stellate cell (qHSC). Recent studies suggest that reversion of the acti...
ORGANISM(S): Homo sapiens 
2015-08-12 | E-GEOD-68001 | biostudies-arrayexpress
TranscriptomicsTranscriptome profile of in vitro produced blastocysts derived from in vitro matured oocytes exposed to exogenous interleukin-6
This study explores the biological role of interleukin-6 (IL-6) as a supplement during in vitro maturation (IVM) of porcine oocytes, aiming to enhance embryonic development and reduce apoptosis following in vitro fertilization (IVF). The objective was to determine whether IL-6 supplementation alters...
ORGANISM(S): Sus scrofa 
2025-06-30 | E-MTAB-15241 | biostudies-arrayexpress
TranscriptomicsCas9 target DNA specificity in vitro and in vivo (S. cerevisiae)
Cas9, a CRISPR RNA-guided nuclease, has been rapidly adopted as a tool for biochemical and genetic manipulation of DNA. Although Cas9 offers remarkable specificity and versatility for genome manipulation, mis-targeted events occur. To extend the understanding of Cas9 target::homology requirements, w...
ORGANISM(S): synthetic construct 
2016-06-10 | E-GEOD-79667 | biostudies-arrayexpress
ProteomicsSpecificity and dynamics of H2O2 detoxification by the cytosolic redox regulatory network as revealed by in vitro reconstitution
The thiol redox state is a decisive functional characteristic of proteins in cell biology. Plasmatic cell compartments maintain a thiol-based redox regulatory network linked to the glutathione/glutathione disulfide couple (GSH/GSSG) and the NAD(P)H system. The basic network constituents are known an...
ORGANISM(S): Escherichia Coli 
2025-01-21 | PXD048374 | JPOST Repository
GenomicsStemNet - in vitro differentiation of human hepatocytes
Integrative epigenomic and transcriptomic characterization of hepatocyte-like cells differentiated in vitro from human induced pluripotent stem cells in comparison with primary human hepatocytes. This study comprises single cell RNA-seq, bulk mRNA-seq, ATAC-seq and RRBS.
EGAS00001004201 | EGA
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