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TranscriptomicsTranscription profiling of hippocapus from eight different inbred mouse strains to identify substantial strain-specific variation in hippocampal gene expression
Mouse inbred strains differ in many aspects of their phenotypes, and it is known that gene expression does so too. This gives us an opportunity to isolate the genetic aspect of variation in expression and compare it to other phenotypic variables. We have investigated these issues using an eight-stra...
ORGANISM(S): Mus musculus 
2007-11-13 | E-GEOD-5429 | biostudies-arrayexpress
TranscriptomicsMouse Inbred Strain Variation Muscle
Variation in gene expression profiles was determined between mouse inbred strains in hindlimb muscle tissue. Strains under investigation were: C57Bl/6, C57Bl/10, CBA, DBA2, and BALB/c.
ORGANISM(S): Mus musculus 
2003-12-09 | E-GEOD-662 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains
We measured genome-wide gene expression of embryonic stem cells derived from eight genetically diverse inbred mouse strains. We derived and cultured cells in LIF+2i media with feeders, and removed feeders prior to RNA collection. All lines were passage 6-8 when RNA was collected. We collected RNA fr...
ORGANISM(S): Mus musculus 
2020-08-13 | E-MTAB-7730 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse inbred strains to identify germline cancer modifiers using parental strain expression mapping
Inherited genetic risk factors play an important role in cancer. However, other than cancer susceptibility genes found in familial cancer syndromes and inherited in a Mendelian fashion, little is known about modifier genes (germline variants that interact with each other and with environmental facto...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7270 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of the Hippocampus from Six Inbred Strains of Mice Suggests Basis for Sex-Specific Susceptibility and Severity of Neurological Disorders
Identifying sex differences in gene expression within the brain is critical for determining why multiple neurological and behavioural disorders differentially affect males and females. Several are more common or severe in males (e.g., autism and schizophrenia) or females (e.g., Alzheimer’s disease...
ORGANISM(S): Mus musculus 
2016-01-06 | E-GEOD-76567 | biostudies-arrayexpress
Genomicsmouse gut metagenome strain:inbred strain | breed:ICR mice
mouse gut metagenome strain:inbred strain | breed:ICR mice Raw sequence reads
PRJNA350594 | ENA
Genomicsmouse gut metagenome strain:inbred strain | breed:ICR mice
mouse gut metagenome strain:inbred strain | breed:ICR mice Raw sequence reads
PRJNA350595 | ENA
TranscriptomicsNovartis 12 Strain Diet Sex Survey
High-fat diets are associated with increased obesity and metabolic disease in mice and humans. Here we used analysis of variance (ANOVA) to scrutinize a microarray data set consisting of 10 inbred strains of mice from both sexes fed atherogenic high-fat and control chow diets. An overall F-test was ...
ORGANISM(S): Mus musculus 
2008-12-10 | E-GEOD-10493 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse inbred strains (8) on Affymetrix exon specific array
Expression profiling of 8 mouse inbred strains on Affymetrix exon specific array
ORGANISM(S): Mus musculus 
2009-06-04 | E-MTAB-86 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hippocampus and retina from two rare inbred mouse models of accelerated neurological senescence ( SAMP8 and SAMP10) and a related wild type strain SAMR1 to study molecular senescence of the retina and hippocampus.
Background: Progressive neurological dysfunction is a key aspect of human aging. Because of underlying differences in the aging of mice and humans, useful mouse models have been difficult to obtain and study. We have used gene-expression analysis and polymorphism screening to study molecular senesce...
ORGANISM(S): Mus musculus 
2007-11-14 | E-GEOD-6238 | biostudies-arrayexpress
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