Induced motor neurons

Show results for

Unknown (2034)
Genomics (327)
Transcriptomics (308)
Proteomics (59)
Other (6)
Metabolomics (4)
Methylation profiling (3)
Genomic (1)
Clinical (1)

Organisms

Homo sapiens (189)
Mus musculus (142)
Aerococcus urinae NBRC 15544 = CCUG 36881 (41)
Alteromonadales (41)
Bacteria (41)
Canis lupus familiaris (41)
Carya cathayensis (41)
Cnidaria (41)
Ectopseudomonas oleovorans CECT 5344 (41)
Ensifer adhaerens (41)
Enterococcus faecalis (41)
Globicatella sanguinis (41)
Halictus scabiosae (41)
Histomonas meleagridis (41)
Human immunodeficiency virus 1 (41)
Mesocricetus auratus (41)
Methylohalobius crimeensis 10Ki (41)
Mus musculus (41)
Rattus norvegicus (25)
Drosophila melanogaster (6)
Caenorhabditis elegans (4)
Microcebus murinus (3)
Pan troglodytes (2)
synthetic construct (2)
Danio rerio (2)
Pan paniscus (1)
Saccharomyces cerevisiae (1)
Aplysia californica (1)
Gallus gallus (1)
Bombyx mori (1)

Organisms

Homo sapiens (135)
Mus musculus (84)
Rattus norvegicus (15)
Drosophila melanogaster (4)
Microcebus murinus (3)
Danio rerio (2)
Aplysia californica (1)
Gallus gallus (1)
Caenorhabditis elegans (1)

Repository

ENA (278)
geo (218)
biostudies-arrayexpress (130)
pride (41)
EGA (15)
MassIVE (9)
iProX (4)
LINCS (4)
MetaboLights (4)
jPOST (3)
dbGaP (1)
PanoramaPublic (1)

Tissue

Brain (12)
Cell culture (10)
Motor neuron (8)
Permanent cell line cell (4)
Stem cell (4)
Pluripotent stem cell (2)
Primary cell (2)
Adipose tissue (1)
Bone marrow (1)
Cerebral cortex (1)
Cerebral cortex neuron (1)
Diploid cell (1)
Embryonic stem cell (1)
Generation of neurons (1)
HiPSC cell (1)
Microglial cell (1)
Multipotent stem cell (1)
Neuron (1)
Neuronal stem cell (1)
Primary neuron (1)
Spinal cord (1)

Disease

Amyotrophic lateral sclerosis (13)
Parkinson's disease (7)
Disease free (2)
SMARD1 (1)
Normal (1)
Colorectal Neoplasms (1)
Frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (1)
Frontotemporal dementia and/or amyotrophic lateral sclerosis-4 (1)
Leigh disease (1)
Parkinsonism (1)

Technology Type

Mass Spectrometry (41)
Shotgun proteomics (21)
Bottom-up proteomics (8)
Data-dependent acquisition (5)
Affinity purification coupled with mass spectrometry proteomics (4)
Top-down proteomics (3)
DNA sequencing (2)
Mass spectrometry (2)
RNA-seq (2)
SWATH-MS (2)
Mass spectrometry (2)
Gel-based experiment (2)
Illumina HiSeq 4000, ILLUMINA (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Data-independent acquisition (1)

Instrument Platform

Illumina NovaSeq 6000 (6)
NextSeq 500 (6)
Orbitrap Fusion Lumos (5)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (3)
NA (2)
NextSeq 2000 (2)
RiboErase Roche (1)
Qiagen RNaesy kit (1)
Qubit 3.0 and Nanodrop Lite (1)
HiSeq X Ten (1)
NextSeq 550 (1)
Illumina HiSeq 2000 (1)
6550 iFunnel Q-TOF LC/MS (1)
Orbitrap Ascend (1)
Orbitrap Fusion (1)
Q Exactive HF (1)
Q Exactive HF-X (1)
Gas Chromatography MS - (1)
Nuclear Magnetic Resonance (NMR) - (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2025 (54)
2026 (43)
2013 (37)
2024 (35)
2023 (28)
2016 (24)
2019 (23)
2014 (22)
2020 (21)
2022 (17)
2015 (16)
2018 (14)
2010 (14)
2017 (14)
2021 (13)
2012 (10)
2008 (8)
2011 (7)
2007 (5)
2009 (4)
2006 (2)
2005 (1)

CHEBI ID

CHEBI:28619 (1)
CHEBI:11805 (1)
CHEBI:17985 (1)
CHEBI:30742 (1)
CHEBI:18139 (1)
CHEBI:60645 (1)
CHEBI:17822 (1)
CHEBI:22660 (1)
CHEBI:27570 (1)
CHEBI:30751 (1)
CHEBI:18186 (1)
CHEBI:28757 (1)
CHEBI:26986 (1)
CHEBI:22652 (1)
CHEBI:16811 (1)
CHEBI:17790 (1)
CHEBI:17234 (1)
CHEBI:17170 (1)
CHEBI:28300 (1)
CHEBI:15347 (1)
CHEBI:16236 (1)
CHEBI:37084 (1)
CHEBI:15676 (1)
CHEBI:16870 (1)
CHEBI:24898 (1)
CHEBI:25017 (1)
CHEBI:15846 (1)
CHEBI:17754 (1)
CHEBI:4167 (1)
CHEBI:28044 (1)

Metabolite Name

2-(2,5-dihydroxy-4-methoxyphenyl)-3,5,6,7-tetrahydroxy-3,4-dihydro-2H-1-benzopyran-4-one; 3-(2,5-dihydroxy-4-methoxyphenyl)-1-(2,3,4,6-tetrahydroxyphenyl)propane-1,2-dione; 3,5,7-trihydroxy-6-methoxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,3,4-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (1)
N-acetyl-L-2-aminoadipate(2-); (1)
VI2Fuc-nLc6; (1)
3',5'-Diiodo-L-thyronine 4'-O-sulfate; (1)
TG(22:1(13Z)/19:2n6/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
TG(15:0/22:2(13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(15:0/22:4(7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)); TG(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)); TG(22:2(13Z,16Z)/15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(22:4(7Z,10Z,13Z,16Z)/15:0/22:4(7Z,10Z,13Z,16Z)); (1)
TG(14:0/15:0/24:0); TG(14:0/24:0/15:0); TG(15:0/14:0/24:0); TG(15:0/16:0/22:0); TG(15:0/18:0/20:0); (1)
Shoyuflavone C; (1)
4-Hydroxycinnamoylagmatine; (1)
Tipranavir; (1)
N-Acetyltryptophan; Methylphenobarbital; Nigellicine; cyclic 6-Hydroxymelatonin; (1)
Sialyllacto-N-tetraose a; Sialyllacto-N-neotetraose c; Sialyllacto-N-tetraose b; LS tetrasaccharide d; Sialyllacto-N-tetraose c; (1)
Ganglioside GD3 (d18:1/12:0); (1)
L-Tryptophan; D-Tryptophan; 3-Hydroxymethylantipyrine; Ethotoin; (Â±)-Tryptophan; (1)
Vinylacetylglycine; Trimethadione; 5-ethyl-5-methyl-2,4-oxazolidinedione; 6-Oxopiperidine-2-carboxylic acid; (1)
Glutamyltryptophan; Tryptophyl-Glutamate; gamma-Glutamyltryptophan; (1)
Norlaudanosoline; Pipermethystine; noroxymorphone; (1)
Ethyl 2-mercaptopropionate; Methyl 3-mercaptobutanoate; Methyl 3-(methylthio)propanoate; Ethyl 2-(methylthio)acetate; Ethyl 3-mercaptopropanoic acid; (1)
Olmesartan; (1)
De-O-methylsterigmatocystin; Aurantricholide B; {3-[2-(3,5-dihydroxyphenyl)ethyl]phenyl}oxidanesulfonic acid; Dihydroresveratrol 3-sulfate; Dihydroresveratrol 4'-sulfate; (1)
1-Isothiocyanato-8-(methylthio)octane; (1)
PA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/24:1(15Z)); PA(24:1(15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
Zizybeoside I; Armillaricin; Benzyl gentiobioside; 15beta-hydroxycyproterone acetate; (1)
6,8-bis[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 8-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-6-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 6-[3,7-dihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-2-(3,4-dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (1)
Simmondsin 2'-ferulate; Astin I; 4-Hydroxytamoxifen-N-glucuronide; 6-{[1-(2-{[3-(3,4-dimethoxyphenyl)-1-hydroxypropylidene]amino}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; 6-{[1-(2-{[2-(3,4-dimethoxyphenyl)ethyl]-C-hydroxycarbonimidoyl}ethyl)-3-methoxy-4-oxocyclohexa-2,5-dien-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid; (1)
Indolelactic acid; 5-Methoxyindoleacetate; Cinnamoylglycine; Edulitine; Methyl 1-methoxy-1H-indole-3-carboxylate; (1)
P-Cresol glucuronide; 2-O-Benzoyl-D-glucose; D-Vacciniin; (1)
(Â±)-Ribaline; 5-Amino-6-(4-hydroxy-2-butenoyl)-2,2-dimethyl-4-chromanone; (1)
CD 1790; (1)
Tetraphyllin B; (1)

First Public Date

2025 (46)
2024 (36)
2026 (32)
2019 (20)
2020 (19)
2014 (19)
2023 (16)
2021 (16)
2022 (15)
2016 (15)
2017 (14)
2018 (12)
2015 (9)
2013 (9)

Study status

Recruiting (1)

Study type

Transcription profiling by array (66)
RNA-seq of coding RNA (32)
ChIP-seq (11)
RNA-seq of coding RNA from single cells (6)
Transcription profiling by tiling array (3)
Methylation profiling by high throughput sequencing (2)
RNA-seq of total RNA (2)
RNA-seq of non coding RNA (2)
ChIP-chip by tiling array (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Other (1)
DNA-seq (1)
Methylation profiling by array (1)
Observational (1)

Release Date

2025 (225)
2023 (225)
2022 (211)
2021 (190)
2024 (186)
2019 (149)
2020 (143)
2018 (122)
2017 (113)
2015 (103)
2016 (97)
2014 (86)
2013 (65)
2026 (44)
2012 (42)
2011 (36)
2010 (35)
2009 (24)
2007 (18)
2008 (15)
2005 (8)
2004 (6)
2006 (5)
2003 (4)
2002 (3)
2001 (2)
2000 (2)
1997 (2)
1999 (1)
1998 (1)

Lab affiliation

1) 1Mitochondrial Neuropathology laboratory, Institut de Neurociències, Universitat Autònoma de Barcelona, Bellaterra, Spain 2) Department of Cellular Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra, Spain. (1)
1Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK (1)
Associate Professor, Neuroscience, The Scripps Research Institute Florida (1)
Associate Professor, New York University - Department of Biology, Center for Genomics & Systems Biology (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Molecular Biomedicine, Roentgenstr. 20, 48149 Muenster, Germany (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Molecular Biomedicine, Röntgenstr. 20, 48149 Münster, Germany (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, the Netherlands. (1)
CECAD Research Center, University of Cologne, Joseph Stelzmann Strasse 26, 50931 Cologne, Germany (1)
Cell biology of neurodegenerative diseases Institute of Anatomy and Cell Biology Ulm University Ulm Germany (1)
Center for RNA Research, Institute for Basic Science, Seoul 08826, S. Korea School of Biological Sciences, Seoul National University, Seoul 08826, S. Korea (1)
Dana Farber Cancer Institute, Boston, MA Harvard Medical School, Boston, MA (1)
Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, North Ryde, NSW, 2109, Australia (1)
Department of Developmental, Molecular and Chemical Biology Tufts University School of Medicine Boston MA 02111 (1)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (1)
Department of Neurology, Nagoya University Graduate School of Medicine (1)
Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Norway (1)
Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands (1)
Dept Biomedical Sciences, School of Medicine and Health Sciences, Institute of Neurosciences, Universitat de Barcelona, E-08036 Barcelona (1)
Director, Biology-Discovery, Quantitative Biosciences, MSD International GmBH (Singapore Branch), Singapore (1)
European Research Institute for the Biology of Ageing, University of Groningen, Groningen, 9713 AV, the Netherlands. (1)
Experimental Systems Immunology (F. Meissner Group) (1)
IRCCS Istituto G Gaslini (1)
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U1258/CNRS UMR 7104/Université de Strasbourg, Illkirch, France (1)
Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany. (1)
Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany (1)
Italian National Institute of Health - Department of Neuroscience (1)
KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), B-3000 Leuven, Belgium; VIB, Center for Brain and Disease Research, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium. (1)
Motor Neuron Disease Research Centre, Macquarie University, NSW, 2113, Australia (1)
Neurodegenerative Diseases Research Group, Korea Brain Research Institute (1)
Normandie Univ, UNIROUEN, Inserm, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Neuropeptides, Neuronal death and Cell plasticity team, 76000 Rouen, France (1)

Location

Italy (1)

Previous page
1 / 275
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 275
Next page

Sort by:

Relevance

Page size

Accelerated high-yield generation of limb-innervating motor neurons from human stem cells

Human pluripotent stem cells are a promising source of diverse cells for developmental studies, cell transplantation, disease modeling, and drug testing. However, their widespread use even for intensely studied cell types like spinal motor neurons, is hindered by the long duration and low yields of...

ORGANISM(S): Homo sapiens

2013-02-06 | E-GEOD-41795 | biostudies-arrayexpress

Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1

Although many distinct mutations in a variety of genes are known to cause Amyotrophic Lateral Sclerosis (ALS), it remains poorly understood how they selectively impact motor neuron biology and whether they converge on common pathways to cause neural degeneration. Here, we have combined reprogramming...

ORGANISM(S): Homo sapiens

2014-02-03 | E-GEOD-54409 | biostudies-arrayexpress

iPSC derived motor neuron cultures from C9ORF72 carriers

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative condition characterized by loss of motor neurons in the brain and spinal cord. Expansions of a hexanucleotide repeat (GGGGCC) in the noncoding region of the C9ORF72 gene are the most common cause of the familial form of ALS (C9-ALS), ...

ORGANISM(S): Homo sapiens

2013-11-07 | E-GEOD-52202 | biostudies-arrayexpress

Transcriptome profiling of severe spinal muscular atrophy mouse embryonic stem cell-derived motor neurons

Proximal spinal muscular atrophy (SMA) is an early onset, autosomal recessive motor neuron disease caused by loss of or mutation in SMN1 (survival motor neuron 1). Despite understanding the genetic basis underlying this disease, it is still not known why motor neurons (MNs) are selectively affected ...

ORGANISM(S): Mus musculus

2014-09-08 | E-GEOD-56284 | biostudies-arrayexpress

Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

Supporting MS data files for paper (doi:10.3389/fncel.2023.1327361) by Watts M.E. et al., titled "Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets". See attached pdf for index of MS files uploaded.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-10-25 | MSV000093190 | MassIVE

Hoxc9 ChIP-seq in differentiating motor neurons

The expression of v5-tagged Hoxc9 is induced and ChIP-seq is used to profile genome-wide occupancy in differentiating motor neurons The differentiation of ventral motor neurons is induced by treating embryonic stem cell cultures with retinoic acid and hedgehog signaling. Here, ChIP-seq is used to pr...

ORGANISM(S): Mus musculus

2010-09-08 | E-GEOD-21812 | biostudies-arrayexpress

Time series gene expression data from adult rat tail MNs following spinal cord transection

Spinal cord injury leads to impaired motor and sensory functions. After spinal cord injury there is a an initial phase of hypo-reflexia followed by a developing hyper-reflexia, often termed spasticity. Previous studies have suggested a relationship between the reappearance of plateau potentials in m...

ORGANISM(S): Rattus norvegicus

2010-05-27 | E-GEOD-19701 | biostudies-arrayexpress

RNA-seq of differentiation stages of motor neurons

induced motor neurons (iMNs) were differentiated from hiPSC line and different timepoints (day 1, 2, 4, 7, 14, 21) were subjected to RNA-seq

ORGANISM(S): Homo sapiens

2025-08-06 | E-MTAB-14359 | biostudies-arrayexpress

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

Ubiquitous expression of ALS-causing mutations in superoxide dismutase 1 (SOD1) provoke non-cell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencing, a cascade of mutant SOD1-dependent, cell type-specific changes are now identified. Initial mutant...

ORGANISM(S): Mus musculus

2015-12-09 | E-GEOD-74724 | biostudies-arrayexpress

Gene expression from human iPSC derived motor neurons.

EGAS00001003785 | EGA

Previous page
1 / 275
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 275
Next page

Sort by:

Relevance

Page size

2743 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

First Public Date

Study status

Study type

Release Date

Lab affiliation

Location

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets