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MetabolomicsB cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size.

The qualities of antibody (Ab) responses provided by B lymphocytes and their plasma cell (PC) descendants are crucial facets of responses to vaccines and microbes. Metabolic processes and products regulate aspects of B cell proliferation and differentiation into germinal center (GC) and PC states...

2026-04-13 | MTBLS13880 | MetaboLights
MetabolomicsThe effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit

Grafting is widely applied in the cultivation of melon. In this study, 'Qinmi No.1' [Cucumis melo L. (QG)] and 'Ribenxuesong' [Cucurbita maxima Duch. (RG)] were used as rootstocks for 'QingxinYangjiaocui' (Cucumis melo L.). The results showed that grafting with...

2023-11-21 | MTBLS8677 | MetaboLights
ProteomicsProbing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines
The GalNAc-type O-glycoproteome is orchestrated by a large family of polypeptide GalNAc-transferase isoenzymes (GalNAc-Ts) with partially overlapping contributions to the O-glycoproteome as well as distinct non-redundant functions. Increasing evidence indicate that individual GalNAc-Ts co-regulate a...
ORGANISM(S): Homo sapiens (Human) 
2018-10-16 | PXD010155 | Pride
Inducible expression Galnac-transferase O-glycosylation Glycoproteomics Mass spectrometry 
TranscriptomicsExpression data from inducible ES stable cell line
In order to identify the effects of the induction of the gene of interest on the mouse ES transcriptome, we performed Affymetrix Gene-Chip hybridization experiments for the inducible not-tagged cell line. Transcriptome analysis of the inducible transgenic mouse ES cell line. The E13 inducible cell l...
ORGANISM(S): Mus musculus 
2012-12-13 | E-GEOD-31166 | biostudies-arrayexpress
GenomicsExpression profiling analysis of an inducible ELF3-expressing and control human bile duct cells [inducible ELF3]
Expression profiling analysis of an inducible ELF3-expressing and control human bile duct cells [inducible ELF3]
PRJNA623269 | ENA
GenomicsExpression profiling of mouse livers with inducible over-expression of microRNA Mir483
Expression profiling of mouse livers with inducible over-expression of microRNA Mir483
PRJNA1078900 | ENA
ProteomicsTime-resolved inducible knock-down of Clp protease subunits in tobacco identifies putative protease substrates
The Clp protease complex in plants is the one with the highest complexity through all life kingdoms. It is composed of 14 nuclear- and plastid-encoded subunits which are allocated in different rings across the complex. The proteolytic ring (P-ring; ClpP3-ClpP6) and non-proteolytic ring (R-ring; ClpR...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-22 | PXD008305 | Pride
Clp protease  chloroplast  protein degradation  protease substrate  nicotiana tabacum  inducible rnai  lc-msms  shotgun proteomics 
GenomicsTime-course inducible NOTCH3-IC expression in SH-SY5Y.
Time-course inducible NOTCH3-IC expression in SH-SY5Y.
PRJNA480495 | ENA
GenomicsXenograft SH-SY5Y tumors with inducible NOTCH3-IC expression.
Xenograft SH-SY5Y tumors with inducible NOTCH3-IC expression.
PRJNA480496 | ENA
TranscriptomicsExpression analysis to identify inducible genes in T cells
Expression microarrays were employed to identify genes induced by phorbol ester and ionomycin stimulation of EL4 cells. EL4 is a murine T cell line. To identify induced genes that were independent of new protein synthesis cells were pre-treated with cycloheximide. This expression study was used in c...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-13278 | biostudies-arrayexpress
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