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MetabolomicsMetabolic disorder and intestinal microflora dysbiosis in chronic inflammatory demyelinating polyradiculoneuropathy

OBJECTIVE: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired immune-mediated neuropathy. Although microbial infection is potentially a contributing factor, a causative link between CIDP and microbial infection remains unclear. There is also no de...

2023-01-16 | MTBLS5828 | MetaboLights
ProteomicsThe pathogenesis of Guillain-Barre syndrome: immunological profiling of physiological fluids
Acute inflammatory demyelinating polyneuropathy (AIDP) - one of the forms of Guillain-Barre syndrome (GBS) - is a rare and severe disorder of the peripheral nervous system that also has an unknown etiology. One of the hallmarks of AIDP pathogenesis is a significantly elevated cerebrospinal fluid (CS...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079941 | MassIVE
ProteomicsThe pathogenesis of Guillain-Barre syndrome: peptidomic profiling of physiological fluids
Acute inflammatory demyelinating polyneuropathy (AIDP) - one of the forms of Guillain-Barre syndrome (GBS) - is a rare and severe disorder of the peripheral nervous system that also has an unknown etiology. One of the hallmarks of AIDP pathogenesis is a significantly elevated cerebrospinal fluid (CS...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079963 | MassIVE
TranscriptomicsTranscriptional changes in demyelinating canine distemper virus encephalitis
Canine distemper virus (CDV)-induced demyelinating leukoencephalitis (CDV-DL) in dogs is a translational animal model for human demyelinating diseases such as multiple sclerosis. The aim of this study was to perform an assumption-free microarray analysis of gene expression in different subgroups of ...
ORGANISM(S): Canis familiaris 
2014-04-23 | E-MEXP-3917 | biostudies-arrayexpress
GenomicsImmunological role of platelets in Theiler’s virus-induced inflammatory demyelinating disease and myocarditis
Immunological role of platelets in Theiler’s virus-induced inflammatory demyelinating disease and myocarditis
PRJNA1065441 | ENA
GenomicsAXL+SIGLEC6+ dendritic cells in cerebrospinal fluid and brain tissues of patients with autoimmune inflammatory demyelinating disease of CNS
AXL+SIGLEC6+ dendritic cells in cerebrospinal fluid and brain tissues of patients with autoimmune inflammatory demyelinating disease of CNS
PRJNA799240 | ENA
ProteomicsDifferential serum proteomics of neuromyelitis spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)
Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are two types of autoimmune-mediated central nervous system (CNS) inflammatory demyelinating diseases that have similar clinical manifestations but with different pathogenesis a...
ORGANISM(S): Homo Sapiens 
2024-12-25 | PXD059225 |
ProteomicsComparison of cerebrospinal fluid proteomics between Demyelinating disease and non-inflammatory neurological controls
Demyelinating disease is a disease of the nervous system in which the nerve demyelinating is the main or primary lesion, and the axon, cell body and glia are relatively lightly damaged. It can occur in the central nervous system or the peripheral nervous system. The demyelinating diseases of central...
ORGANISM(S): Homo Sapiens 
2020-12-09 | PXD023027 |
ProteomicsComplement profiling on sural nerves of patients with chronic inflammatory demyelinating polyneuropathy
Overall, 55 sural nerve biopsies from patients with CIDP (n=36) and CIDP-variants (n=18) were included into the study. Immunohistochemical analysis of the sural nerve specimens showed an aberrant deposition of terminal complement complex C5b-9 on endoneural capillaries in 52 (94%) of patients in add...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD056286 | Pride
Proteomics Gene expression Chronic inflammatory demyelinating polyneuropathy  complement profiles  sural nerve 
TranscriptomicsNext Generation Sequencing of Pattern II Demyelinating Brain Lesions from a Multiple Sclerosis Patient
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system with marked heterogeneity in several aspects including pathological processes. Four histopathological patterns of MS have been described. Pattern II is characterized by infiltrating macrophages and T-cel...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-60942 | biostudies-arrayexpress
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